Evidence map›Paper›PMID 40738964›Full record

ReviewProstate cancer and prostatic diseases2026

Prostate specific membrane antigen focal ablation imaging (PSMA-FAB).

Egesta Lopci, Massimo Lazzeri, Vittorio Fasulo, Davide Maffei, Pier Paolo Avolio, Alessandro Tallari, Stefano Moretto, Ludovica Cella, Marcello Rodari, Federica Mrakic Sposta and 3 more

Abstract readReview
In one paragraph

Review in Prostate cancer and prostatic diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Egesta LopciNuclear Medicine, IRCCS-Humanitas Research Hospital, Rozzano, Italy. egesta.lopci@cancercenter.humanitas.it.ORCID http://orcid.org/0000-0001-9732-1094
Massimo LazzeriUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0000-0002-4411-3715
Vittorio FasuloUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.
Davide MaffeiUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.
Pier Paolo AvolioUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.
Alessandro TallariUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.
Stefano MorettoUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.
Ludovica CellaUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.
Marcello RodariNuclear Medicine, IRCCS-Humanitas Research Hospital, Rozzano, Italy.
Federica Mrakic SpostaRadiology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.
Paolo CasaleUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0000-0002-7899-5736
Nicolò Maria BuffiUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.
Giovanni LughezzaniUrology, IRCCS-Humanitas Research Hospital, Rozzano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Prostate Imaging after Focal Ablation (PI-FAB) score has been recently proposed for scoring the appearance on multiparametric magnetic resonance imaging (mpMRI) of prostate cancer after focal therapy. The progressive implementation of prostate specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) into the management of prostate cancer has revolutionized the diagnostic work-up and inspired our proposal for a dedicated PSMA Focal Ablation Imaging (PSMA-FAB) scoring system. Based on pre- and post-treatment imaging, the classification is categorized into: PSMA-FAB 1 (continue monitoring); PSMA-FAB2 (assess PSA kinetics and MRI, with biopsy to be considered in case of suspicion); and PSMA-FAB 3 (recommend biopsy). Furthermore, a combined Focal-therapy Imaging Response Evaluation Score (FIRE-SCORE) embedding PI-FAB and PSMA-FAB scores is suggested to help patient's management at follow up.

Indexed as

Antigens, SurfaceGlutamate Carboxypeptidase IIProstatic NeoplasmsHumansMaleMultiparametric Magnetic Resonance ImagingPositron Emission Tomography Computed TomographyProstate-Specific AntigenAntigens, SurfaceFOLH1 protein, humanGlutamate Carboxypeptidase IIProstate-Specific Antigen

Identifiers

PMID40738964
PMCPMC13472940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.