Evidence map›Paper›PMID 40738554›Full record

SynthesisThe Lancet. Public health2025

Drivers of human papillomavirus vaccine uptake in migrant populations and interventions to improve coverage: a systematic review and meta-analysis.

Michiyo Iwami, Oumnia Bouaddi, Mohammad S Razai, Rania Mansour, Beatriz Morais, Nafeesa Mat Ali, Alison F Crawshaw, Sainabou Bojang, Farah Seedat, Anna Deal and 9 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Lancet. Public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
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  9. Article
  10. Review
  11. Crossing Borders: SRH Challenges Among Immigrant and Minority Adolescents.International journal of environmental research and public health · 2025
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Michiyo IwamiThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Oumnia BouaddiMohammed VI International School of Public Health, Mohammed VI University of Sciences and Health, Casablanca, Morocco; Department of Public Health and Clinical Research, Mohammed VI Center for Research and Innovation, Rabat, Morocco; Barcelona Institute for Global Health, Hospital Clinic - University of Barcelona, Barcelona, Spain.
Mohammad S RazaiThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK; Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Rania MansourThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK; Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA.
Beatriz MoraisInstitute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Nafeesa Mat AliInstitute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Alison F CrawshawThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK; Prevention, Inequalities and Commissioning, City and Hackney Public Health Team, Hackney Council, London, UK.
Sainabou BojangThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Farah SeedatThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Anna DealThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Sophie WebbInstitute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Jessica CarterThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Nathaniel AsprayThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Nuria Sanchez ClementeThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Juan Arroyo-LagunaInstitute of Social Analytics and Strategic Intelligence Pulso PUCP, Faculty of Social Sciences, Pontifical Catholic University of Peru, Lima, Peru.
Sanjeev KrishnaInstitute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK; Institut Für Tropenmedizin, Eberhard Karls Universität Tübingen and German Center for Infection Research, Tübingen, Germany.
Yolanda AugustinInstitute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Henry M StainesInstitute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Sally HargreavesThe Migrant Health Research Group, Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, UK. Electronic address: s.hargreaves@sgul.ac.uk.

Funding

Department of Health NIHR300072Wellcome Trust 318501
6 · The paper itself

Abstract

backgroundWHO's Cervical Cancer Elimination Initiative has set a target for 90% of girls to be fully vaccinated against human papillomavirus (HPV) by the age of 15 years by 2030, to substantially reduce deaths from cervical and other HPV-related cancers. However, progress has been slow, with only 27% global vaccine coverage in 2023. Migrants are an under-immunised group globally for many vaccine-preventable diseases, with data showing that they experience a high burden of HPV infection and widespread HPV under-immunisation. We aimed to identify drivers of HPV vaccine uptake in migrants, as well as assess uptake and explore recommended approaches, strategies, and best practices to promote uptake in migrant communities.

methodsIn this systematic review and meta-analysis, we searched seven databases and several grey literature sources for information published in any language between Jan 1, 2006, and Dec 4, 2024, on the drivers of HPV vaccine uptake among migrants globally. Defining migrants as foreign-born nationals, we included qualitative and quantitative cross-sectional studies, cohort studies, and randomised controlled trials focused on first-generation and second-generation migrants and excluded studies of internal migrants. Outcomes were frequency and percentage of HPV vaccine uptake; factors positively or negatively influencing uptake; and recommended approaches, strategies, and best practices to promote uptake as reported by study authors or participants. We conducted a hybrid thematic analysis using the WHO Behavioural and Social Drivers of Vaccination model to map drivers of uptake, and a random-effects meta-analysis to calculate pooled estimates of uptake. Risk of bias was assessed using Joanna Briggs Institute checklists. This study is registered with PROSPERO, CRD42022347513.

findingsOf 3562 records returned by the search, 117 studies were included in the analysis, involving 5 638 838 participants across 16 countries and one territory, of whom 933 189 were first-generation and second-generation migrants. The pooled estimates of HPV vaccine uptake were 23·0% (95% CI 10·0-44·0; I

interpretationWe show that migrants globally face complex individual, family and social, and provider-level and system-level barriers to HPV vaccination, resulting in low uptake of HPV vaccines and missed opportunities for protection. In many low-income and middle-income countries, there is little to no availability of vaccines and/or the recipient must pay for them. Achieving global commitments to universal and equitable immunisation across the life course-and making progress towards cervical cancer elimination-requires these barriers to be addressed through multipronged strategies. Collaborative efforts with migrant communities are essential to co-develop effective, tailored delivery models that meet their unique needs.

fundingThe National Institute for Health and Care Research, the Academy of Medical Sciences, and the Medical Research Council.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesPatient Acceptance of Health CareTransients and MigrantsVaccination CoverageAdolescentFemaleHumansUterine Cervical NeoplasmsPapillomavirus Vaccines

Identifiers

PMID40738554
PMCPMC7618757

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.