ReviewJournal of advanced research2026
Research progress on blood therapy for anti-aging.
Review in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBlood is best known for its critical roles such as oxygen distribution, nutrient transport, hemostasis, and immune surveillance. However, its impact on biological aging remains unknown. Accumulating evidence indicates that interventions targeting the vascular system may decelerate or even reverse the aging process, such as heterochronic parabiosis (HPB), therapeutic plasma exchange (TPE), platelet-rich plasma (PRP) injection, extracellular vesicles (EVs) transfusion, and platelet factor transfusion. AIM OF REVIEW: Our aim is to elucidate the precise interactions between blood components and the bodily aging process, in order to facilitate the development of novel blood therapy strategies to combat aging and prolong healthy lifespan. KEY SCIENTIFIC CONCEPTS OF REVIEW: Here we summarize age-related changes in circulating factors and cells of blood system, then introduce five anti-aging therapy methods targeting the blood, as well as their anti-aging effects and the components responsible for the effects. We also discuss the possible anti-aging mechanisms of these blood therapies and summarize the limitations of these therapies and the challenges in translating them to clinical practice. To address these challenges and limitations, we also propose several emerging research trends in blood-based therapies for anti-aging.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.