ReviewCurrent opinion in microbiology2025
Brownian ratchet mechanisms for carboxysome positioning in bacteria.
Review in Current opinion in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Article
- Bacterial Sentience Is Determined by the Stochastic, Chaotic, and Deterministic Behavior of Cytoplasmic Particles.Current issues in molecular biology · 2026Review
- Polyphosphate acts as an architectural regulator of carbon fixation and nucleoid structure in cyanobacteria.bioRxiv : the preprint server for biology · 2026Article
- The kinetics and mobility of a ParA ATPase drive carboxysome distribution inbioRxiv : the preprint server for biology · 2026Article
- Recent insights into α-carboxysome structure, mechanism, and assembly.Journal of bacteriology · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
ParA-type ATPases position multiple cellular cargos in bacteria. DNA partitioning by ParA is proposed to occur via a Brownian ratchet mechanism. It is unclear whether this mechanism accounts for the distribution of other ParA-positioned cargos. Among these cargos are bacterial microcompartments (BMCs), protein-based organelles that encapsulate metabolic components in bacteria. The most widely studied BMC is the carboxysome, which sequesters carbon fixation machinery and contributes significantly to global carbon fixation. Carboxysomes are spatially regulated by the Maintenance of Carboxysome Distribution (Mcd) system. Similarities between the McdA protein and the ParA ATPase family proteins have led to the proposal of a Brownian ratchet-based positioning mechanism for carboxysomes. Here, we describe ParA-type ATPases, the proposed variations of the Brownian ratchet mechanism, and how they may account for carboxysome organization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.