Evidence map›Paper›PMID 40737766›Full record

ArticleSchizophrenia research2025

Victimization and engagement with the legal system among individuals at clinical high risk (CHR) for psychosis.

Ashley Du, Leda Kennedy, Jean Addington, Carrie E Bearden, Tyrone D Cannon, Ricardo Carrion, Matcheri Keshavan, Daniel H Mathalon, Diana O Perkins, William Stone and 3 more

Abstract read
In one paragraph

Article in Schizophrenia research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ashley DuDepartment of Psychiatry, UCSD, San Diego, CA, United States of America. Electronic address: awdu@health.ucsd.edu.
Leda KennedyDepartment of Psychiatry, UCSD, San Diego, CA, United States of America. Electronic address: lekennedy@health.ucsd.edu.
Jean AddingtonDepartment of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada. Electronic address: jmadding@ucalgary.ca.
Carrie E BeardenDepartment of Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, CA, United States of America. Electronic address: CBearden@mednet.ucla.edu.
Tyrone D CannonDepartment of Psychology, Yale University, New Haven, CT, United States of America. Electronic address: tyrone.cannon@yale.edu.
Ricardo CarrionDepartment of Psychiatry, Zucker Hillside Hospital, Long Island, NY, United States of America. Electronic address: rcarrion@northwell.edu.
Matcheri KeshavanDepartment of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center and Massachusetts Mental Health Center, Boston, MA, United States of America. Electronic address: mkeshava@bidmc.harvard.edu.
Daniel H MathalonDepartment of Psychiatry, UCSF, and SFVA Medical Center, San Francisco, CA, United States of America. Electronic address: Daniel.Mathalon@ucsf.edu.
Diana O PerkinsDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC, United States of America. Electronic address: Diana_Perkins@med.unc.edu.
William StoneDepartment of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center and Massachusetts General Hospital, Boston, MA, United States of America. Electronic address: wstone@bidmc.harvard.edu.
Elaine F WalkerDepartments of Psychology and Psychiatry, Emory University, Atlanta, GA, United States of America. Electronic address: psyefw@emory.edu.
Scott W WoodsDepartment of Psychiatry, Yale University, New Haven, CT, United States of America. Electronic address: scott.woods@yale.edu.
Kristin S CadenheadDepartment of Psychiatry, UCSD, San Diego, CA, United States of America. Electronic address: kcadenhead@health.ucsd.edu.

Funding

1/9 Predictors and Mechanisms of Conversion to PsychosisU01MH081902 · NIMH · YALE UNIVERSITY · PI CANNON, TYRONE D · 2008 to 2018
$12.4M
5/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082004 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PERKINS, DIANA O. · 2008 to 2018
$7.5M
Administrative Supplement Harmonization of At Risk Multisite Observational Networks for Youth(HARMONY)U01MH081928 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI STONE, WILLIAM SETH · 2008 to 2018
$7.1M
4/9-Predictors and Mechanisms of Conversion to PsychosisU01MH081857 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI CORNBLATT, BARBARA A. · 2008 to 2018
$6.2M
8/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082022 · NIMH · YALE UNIVERSITY · PI WOODS, SCOTT W · 2008 to 2018
$6.0M
2/9 - Predictors and Mechanisms of Conversion to PsychosisU01MH081988 · NIMH · EMORY UNIVERSITY · PI WALKER, ELAINE FRAN · 2008 to 2018
$5.4M
6/9-Predictors and Mechanisms of Conversion to PsychosisU01MH081944 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CADENHEAD, KRISTIN S. · 2008 to 2018
$4.9M
"7/9" Predictors and Mechanisms of Conversion to PsychosisU01MH081984 · NIMH · UNIVERSITY OF CALGARY · PI ADDINGTON, JEAN M · 2008 to 2018
$4.2M
9/9-Predictors and Mechanisms of Conversion to PsychosisU01MH076989 · NIMH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MATHALON, DANIEL H · 2014 to 2018
$3.9M
NIMH NIH HHS U01 MH076989NIMH NIH HHS U01MH076989NIMH NIH HHS U01 MH081857NIMH NIH HHS U01 MH081902NIMH NIH HHS U01MH081902NIMH NIH HHS U01 MH081928NIMH NIH HHS U01MH081928NIMH NIH HHS U01 MH081944NIMH NIH HHS U01MH081944NIMH NIH HHS U01 MH081984NIMH NIH HHS U01MH081984NIMH NIH HHS U01 MH081988NIMH NIH HHS U01MH081988NIMH NIH HHS U01 MH082004NIMH NIH HHS U01MH082004NIMH NIH HHS U01 MH082022NIMH NIH HHS U01MH082022NIMH NIH HHS UO1MH081857
6 · The paper itself

Abstract

backgroundDespite findings of more victimization and legal issues in individuals with psychotic illness, little is known about this history among youth at clinical high-risk for psychosis (CHR). Further, it is unclear whether certain demographic, clinical, functional, or diagnostic patterns exist among CHR youth who report victimization and/or crime/legal engagement.

methodsParticipants (N = 684 CHR, N = 95 healthy controls) were part of the North American Prodromal Longitudinal Study-3 (NAPLS-3). CHR participants were grouped according to whether they endorsed/did not endorse a history of being a victim of crime or being engaged with crime (committed, accused or convicted)/the legal system. Differences in clinical symptoms, functioning, diagnoses, and life-risk factors were examined in each of the groups. Follow-up binary logistic regressions were employed to assess variables associated with victimization and crime/legal engagement.

resultsCHR youth were significantly more likely to report being a victim or perpetrator of crime compared to healthy controls and those with this history were more likely to have multiple risk factors for violence and comorbid mental illness. Grandiosity was significantly associated with both a history of victimization and crime/legal engagement while other symptoms were at a trend level. Age and historical risk factors were the most strongly associated with later victimization and engagement with the legal system, even when controlling for attenuated psychosis symptoms. DISCUSSION: Risk factors among CHR youth with a legal history closely resemble those faced in the general population. These findings speak to the importance of assessment and intervention for youth with historical/environmental adversity and legal history.

Indexed as

Crime VictimsPsychotic DisordersAdolescentAdultFemaleHumansLongitudinal StudiesMaleProdromal SymptomsRisk FactorsYoung AdultClinical high-risk (CHR) psychosisLegal systemVictimization

Identifiers

PMID40737766
PMCPMC13580620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.