Evidence map›Paper›PMID 40737736›Full record

ArticleClinical biomechanics (Bristol, Avon)2025

Determining the individual relationship between the step width and peak knee adduction moment during stepping in medial knee osteoarthritis.

Raziyeh Baghi, Wei Yin, Subham Badhyal, Ahmed Ramadan, Giovanni Oppizzi, Zongpan Li, Peter Bowman, Frank Henn, Li-Qun Zhang

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Article in Clinical biomechanics (Bristol, Avon), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Raziyeh BaghiDepartment of Physical Therapy & Rehabilitation Science, University of Maryland Baltimore, Baltimore, MD, United States.
Wei YinDepartment of Physical Therapy & Rehabilitation Science, University of Maryland Baltimore, Baltimore, MD, United States.
Subham BadhyalDepartment of Physical Therapy & Rehabilitation Science, University of Maryland Baltimore, Baltimore, MD, United States.
Ahmed RamadanDepartment of Physical Therapy & Rehabilitation Science, University of Maryland Baltimore, Baltimore, MD, United States.
Giovanni OppizziDepartment of Physical Therapy & Rehabilitation Science, University of Maryland Baltimore, Baltimore, MD, United States; Fischell Department of Bioengineering, University of Maryland College Park, College Park, MD, United States.
Zongpan LiDepartment of Physical Therapy & Rehabilitation Science, University of Maryland Baltimore, Baltimore, MD, United States.
Peter BowmanDepartment of Physical Therapy & Rehabilitation Science, University of Maryland Baltimore, Baltimore, MD, United States.
Frank HennDepartment of Orthopaedics, University of Maryland Baltimore, Baltimore, MD, United States.
Li-Qun ZhangDepartment of Physical Therapy & Rehabilitation Science, University of Maryland Baltimore, Baltimore, MD, United States; Fischell Department of Bioengineering, University of Maryland College Park, College Park, MD, United States; Department of Orthopaedics, University of Maryland Baltimore, Baltimore, MD, United States. Electronic address: l-zhang@som.umaryland.edu.

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
ACL HHS 90ARHF0009ACL HHS 90REMM0001NIA NIH HHS P30 AG028747
6 · The paper itself

Abstract

backgroundStep-width modification can reduce peak knee adduction moment during gait in individuals with knee osteoarthritis, but determining optimal subject-specific step-width without testing multiple discrete positions remains a clinical challenge.

methodWe investigated step-width's relationship with peak knee adduction moment in 14 individuals with medial knee osteoarthritis and 14 healthy controls using a robotic stepping system with motorized footplates moving between narrow, neutral, and wide step-widths. We analyzed peak knee adduction moment-step width relationship slopes and compared peak three-dimensional knee moments between all stepping conditions using repeated-measure ANOVA analysis.

findingsBoth groups showed negative peak knee adduction moment-step width slopes, indicating reduced peak knee adduction moment with wider step-widths (knee osteoarthritis: P = 0.019, Controls: P = 0.016), with knee osteoarthritis group showing significantly higher slope and intercept values (P < 0.01, P < 0.001). Both groups demonstrated lower peak knee adduction moment and knee adduction moment impulse with wide step-width versus narrow and neutral step-widths (all P < 0.001). Lower peak knee adduction moment during wide step-width significantly correlated with increased tibia medial tilt (P < 0.001), increased footplate lateral reaction force (P = 0.023), reduced footplate inversion reaction torque (P < 0.001), reduced stepping speed (P = 0.022), and absence of knee osteoarthritis (P < 0.001).

interpretationWider step-width effectively reduces peak knee adduction moment and knee adduction moment impulse during stepping. The robotic stepping system enables precise subject-specific step-width determination using peak knee adduction moment-step width relationships, potentially offering individualized rehabilitation strategies for knee osteoarthritis management.

Indexed as

GaitKnee JointOsteoarthritis, KneeAdultAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedRange of Motion, ArticularRoboticsWalkingBiomechanicsKinematics and kineticsKnee adduction momentKnee osteoarthritisRehabilitation

Identifiers

PMID40737736
PMCPMC12368841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.