Evidence map›Paper›PMID 40737700›Full record

Trial reportJMIR medical education2025

A Large-Scale Multispecialty Evaluation of Web-Based Simulation in Medical Microbiology Laboratory Education: Randomized Controlled Trial.

Lei Xu, Xichuan Deng, Tingting Chen, Nan Lu, Yuran Wang, Jia Liu, Yanan Guo, Zeng Tu, Yuxin Nie, Yeganeh Hosseini and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in JMIR medical education, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lei XuDepartment of Pathogenic Biology, School of Basic Medicine, Chongqing Medical University, 1 Medical College Road, Yuzhong District, Chongqing, China, 86 2368485288.ORCID 0000-0002-5959-8735
Xichuan DengPathogen Biology and Immunology Laboratory, Experimental Teaching and Management Center, Chongqing Medical University, Chongqing, China.ORCID 0000-0002-7836-8708
Tingting ChenPathogen Biology and Immunology Laboratory, Experimental Teaching and Management Center, Chongqing Medical University, Chongqing, China.ORCID 0000-0002-0089-9402
Nan LuDepartment of Pathogenic Biology, School of Basic Medicine, Chongqing Medical University, 1 Medical College Road, Yuzhong District, Chongqing, China, 86 2368485288.ORCID 0000-0002-3056-7871
Yuran WangDepartment of Pathogenic Biology, School of Basic Medicine, Chongqing Medical University, 1 Medical College Road, Yuzhong District, Chongqing, China, 86 2368485288.ORCID 0009-0006-5555-4256
Jia LiuPathogen Biology and Immunology Laboratory, Experimental Teaching and Management Center, Chongqing Medical University, Chongqing, China.ORCID 0000-0003-0274-7581
Yanan GuoDepartment of Pathogenic Biology, School of Basic Medicine, Chongqing Medical University, 1 Medical College Road, Yuzhong District, Chongqing, China, 86 2368485288.ORCID 0000-0002-2072-8213
Zeng TuDepartment of Pathogenic Biology, School of Basic Medicine, Chongqing Medical University, 1 Medical College Road, Yuzhong District, Chongqing, China, 86 2368485288.ORCID 0000-0002-0329-4097
Yuxin NieThe Second Clinical College, Chongqing Medical University, Chongqing, China.ORCID 0009-0005-7247-3768
Yeganeh HosseiniCollege of International Education, Chongqing Medical University, Chongqing, China.ORCID 0009-0000-1695-2602
Yonglin HeDepartment of Pathogenic Biology, School of Basic Medicine, Chongqing Medical University, 1 Medical College Road, Yuzhong District, Chongqing, China, 86 2368485288.ORCID 0000-0002-6501-7685

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Traditional laboratory teaching of pathogenic cocci faces challenges in biosafety and standardization across medical specialties. While virtual simulation shows promise, evidence from large-scale, multidisciplinary studies remains limited. Objective: The study aims to evaluate the effectiveness of integrating virtual simulation with traditional laboratory practice in enhancing medical microbiology education, focusing on the identification of biosafety level 2 pathogenic cocci. The study assessed improvements in student performance, theoretical understanding, laboratory safety, and overall satisfaction, while achieving standardization and cost reduction across multiple medical specialties. Methods: This randomized controlled trial involved 1282 medical students from 9 specialties. The experimental group (n=653) received virtual simulation training-featuring interactivity and intelligent feedback-prior to traditional laboratory practice, while the control group (n=629) did not receive such training. Our virtual system focused on biosafety level 2 pathogenic cocci identification with dynamic specimen generation. Results: The experimental group showed significantly improved performance across specialties (P<.05 for each specialty), particularly in clinical medicine, in which the experimental group score was 89.88 (SD 13.09) and the control group score was 68.34 (SD 17.23; P<.001). The students reported that virtual simulation enhanced their theoretical understanding (1268/1282, 98.9%) and laboratory safety (1164/1282, 90.8%) while helping them achieve standardization (790/1282, 61.6%,) and cost reduction (957/1282, 74.6%). Overall student satisfaction reached 97.2% (1246/1282), with distinct learning patterns observed across specialties. The test scores were significantly higher in the experimental group, with a mean of 80.82 (SD 17.10), compared to the control group, with a mean of 67.45 (SD 16.81). Conclusions: This large-scale study demonstrates that integrating virtual simulation with traditional methods effectively enhances medical microbiology education, providing a standardized, safe, and cost-effective approach for teaching high-risk pathogenic experiments.

Indexed as

MicrobiologySimulation TrainingEducational MeasurementEducation, MedicalFemaleHumansInternetMaleStudents, Medicalblended learningcost-effectivenesslaboratory safetymedical educationmultispecialty evaluationpathogenic coccivirtual simulation

Identifiers

PMID40737700
PMCPMC12310184

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.