Evidence map›Paper›PMID 40737494›Full record

ArticleJMIR diabetes2025

"Digital Clinicians" Performing Obesity Medication Self-Injection Education: Feasibility Randomized Controlled Trial.

Sean Coleman, Caitríona Lynch, Hemendra Worlikar, Emily Kelly, Kate Loveys, Andrew J Simpkin, Jane C Walsh, Elizabeth Broadbent, Francis M Finucane, Derek O' Keeffe

Abstract read
In one paragraph

Article in JMIR diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sean ColemanDepartment of Diabetes, Endocrinology, and Metabolism, University Hospital Galway, Newcastle Rd, Galway, H91 YR71, Ireland, 353 851604880.ORCID http://orcid.org/0000-0003-0770-2219
Caitríona LynchDepartment of Diabetes, Endocrinology, and Metabolism, University Hospital Galway, Newcastle Rd, Galway, H91 YR71, Ireland, 353 851604880.ORCID http://orcid.org/0000-0001-6868-5489
Hemendra WorlikarSchool of Medicine, University of Galway, Galway, Ireland.ORCID http://orcid.org/0000-0001-6593-2616
Emily KellySchool of Medicine, University of Galway, Galway, Ireland.ORCID http://orcid.org/0009-0001-6789-1544
Kate LoveysSchool of Psychology, University of Auckland, Auckland, New Zealand.ORCID http://orcid.org/0000-0003-0694-4830
Andrew J SimpkinSchool of Mathematics and Statistical Science, University of Galway, Galway, Ireland.ORCID http://orcid.org/0000-0002-4975-444X
Jane C WalshSchool of Psychology, University of Galway, Galway, Ireland.ORCID http://orcid.org/0000-0001-5476-1348
Elizabeth BroadbentSchool of Psychology, University of Auckland, Auckland, New Zealand.ORCID http://orcid.org/0000-0003-3626-9100
Francis M FinucaneDepartment of Diabetes, Endocrinology, and Metabolism, University Hospital Galway, Newcastle Rd, Galway, H91 YR71, Ireland, 353 851604880.ORCID http://orcid.org/0000-0002-5374-7090
Derek O' KeeffeDepartment of Diabetes, Endocrinology, and Metabolism, University Hospital Galway, Newcastle Rd, Galway, H91 YR71, Ireland, 353 851604880.ORCID http://orcid.org/0000-0001-8501-2382

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Artificial intelligence (AI) chatbots have shown competency in a range of areas, including clinical note taking, diagnosis, research, and emotional support. An obesity epidemic, alongside a growth in novel injectable pharmacological solutions, has put a strain on limited resources. Objective: This study aimed to investigate the use of a chatbot integrated with a digital avatar to create a "digital clinician." This was used to provide mandatory patient education for those beginning semaglutide once-weekly self-administered injections for the treatment of overweight and obesity at a national center. Methods: A "digital clinician" with facial and vocal recognition technology was generated with a bespoke 10- to 15-minute clinician-validated tutorial. A feasibility randomized controlled noninferiority trial compared knowledge test scores, self-efficacy, consultation satisfaction, and trust levels between those using the AI-powered clinician avatar onsite and those receiving conventional semaglutide education from nursing staff. Attitudes were recorded immediately after the intervention and again at 2 weeks after the education session. Results: A total of 43 participants were recruited, 27 to the intervention group and 16 to the control group. Patients in the "digital clinician" group were significantly more knowledgeable postconsultation (median 10, IQR 10-11 vs median 8, IQR 7-9.3; P<.001). Patients in the control group were more satisfied with their consultation (median 7, IQR 6-7 vs median 7, IQR 7-7; P<.001) and had more trust in their education provider (median 7, IQR 4.8-7 vs median 7, IQR 7-7; P<.001). There was no significant difference in reported levels of self-efficacy (P=.57). 81% (22/27) participants in the intervention group said they would use the resource in their own time. Conclusions: Bespoke AI chatbots integrated with digital avatars to create a "digital clinician" may perform health care education in a clinical environment. They can ensure higher levels of knowledge transfer yet are not as trusted as their human counterparts. "Digital clinicians" may have the potential to aid the redistribution of resources, alleviating pressure on bariatric services and health care systems, the extent to which remains to be determined in future studies.

Indexed as

AIartificial intelligenceautomateautomationchatbotschatGPTclinical educationdeep learningdigital clinicianfeasibility studieslarge language modelsmachine-human interfacemachine learningmedicationMLnatural language processingNLPobesityrandomized controlled trialsRCTstrustvirtual human

Identifiers

PMID40737494
PMCPMC12309861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.