Evidence map›Paper›PMID 40737485›Full record

ArticleAmerican journal of respiratory cell and molecular biology2025

Siglec-F Deficiency Prevents Fibrosis after Bleomycin-induced Acute Lung Injury.

Marika Orlov, Naoko Hara, Sunad Rangarajan, Ana M Jaramillo, Qihua Ye, Yuliana M Romo-Perez, Kenny Ngo, James C NeeDell, Anna Q Harder, Fan Jia and 9 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Marika OrlovUniversity of Colorado School of Medicine Denver, Colorado.ORCID 0000-0003-1961-0813
Naoko HaraUniversity of Colorado School of Medicine Denver, Colorado.
Sunad RangarajanUniversity of Colorado School of Medicine Denver, Colorado.ORCID 0000-0001-5313-4828
Ana M JaramilloUniversity of Colorado School of Medicine Denver, Colorado.
Qihua YeUniversity of Colorado School of Medicine Denver, Colorado.
Yuliana M Romo-PerezNational Jewish Health Denver, Colorado.
Kenny NgoUniversity of Colorado School of Medicine Denver, Colorado.
James C NeeDellUniversity of Colorado School of Medicine Denver, Colorado.
Anna Q HarderUniversity of Colorado School of Medicine Denver, Colorado.
Fan JiaNational Jewish Health Denver, Colorado.
Brian VestalNational Jewish Health Denver, Colorado.
Rachel Z BlumhagenUniversity of Colorado School of Medicine Denver, Colorado.
Ting Hui TuNational Jewish Health Denver, Colorado.
Jazalle McClendonNational Jewish Health Denver, Colorado.
Alexandra L McCubbreyUniversity of Colorado School of Medicine Denver, Colorado.
Bradford J SmithUniversity of Colorado Denver, Anschutz Medical Campus Aurora, Colorado.
David A SchwartzUniversity of Colorado School of Medicine Denver, Colorado.
William J JanssenUniversity of Colorado School of Medicine Denver, Colorado.ORCID 0000-0002-6397-3454
Christopher M EvansUniversity of Colorado School of Medicine Denver, Colorado.ORCID 0000-0001-5600-7314

Funding

MULTIDISCIPLINARY RESPIRATORY DISEASES RESEARCH TRAININGT32HL007085 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM, LISA A MAIER · 1985 to 2026
$21.6M
Targeting early events in MUC5B-driven lung injury and fibrosisP01HL162607 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI David Albert Schwartz · 2023 to 2026
$12.4M
Role of Mucin in Lung Homeostasis and PathophysiologyR01HL080396 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Christopher M Evans · 2009 to 2026
$8.6M
Lung Macrophage Programming in Acute Lung InjuryR35HL140039 · NHLBI · NATIONAL JEWISH HEALTH · PI JANSSEN, WILLIAM · 2018 to 2024
$6.4M
Mechanisms of lung macrophage programming by MUC5B during health and diseaseR01HL130938 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI EVANS, CHRISTOPHER M · 2016 to 2025
$5.2M
Preclinical Pulmonary Fibrosis, an opportune rare disease cohortUH3HL151865 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI SCHWARTZ, DAVID ALBERT · 2022 to 2025
$4.3M
Molecular Determinants of Usual Interstitial Pneumonia (UIP)R01HL158668 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI David Albert Schwartz, Ivana V Yang · 2022 to 2026
$3.5M
Roles for interstitial and airspace macrophages in resolution of pulmonary inflammationR01HL149741 · NHLBI · NATIONAL JEWISH HEALTH · PI HENSON, PETER M, REDENTE, ELIZABETH FRANCES · 2020 to 2023
$3.0M
Genes and Transcripts that Interact with MUC5B in Pulmonary FibrosisR01HL149836 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI CLOUTHIER, DAVID E., SCHWARTZ, DAVID ALBERT · 2020 to 2023
$3.0M
Predicting and Preventing Ventilator-Induced Lung InjuryR01HL151630 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI SMITH, BRADFORD J · 2021 to 2025
$2.9M
Airway Basal Progenitor Dysfunction in the Detection, Progression and Pathogenesis of Early COPDR01HL164555 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Moumita Ghosh, RICHARD W VANDIVIER · 2023 to 2026
$2.8M
Preclinical Pulmonary Fibrosis, an opportune rare disease cohortUG3HL151865 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI SCHWARTZ, DAVID ALBERT · 2020 to 2021
$1.7M
BLRD VA I01 BX005295BLRD VA I01 BX005343National Science Foundation 2225554NHLBI NIH HHS F32 HL172725NHLBI NIH HHS K99 HL165072NHLBI NIH HHS K99HL165072NHLBI NIH HHS P01 HL162607NHLBI NIH HHS P01HL162607NHLBI NIH HHS R00 HL165072NHLBI NIH HHS R01 HL080396NHLBI NIH HHS R01HL080396NHLBI NIH HHS R01 HL130938NHLBI NIH HHS R01HL130938NHLBI NIH HHS R01HL14974NHLBI NIH HHS R01 HL149741NHLBI NIH HHS R01 HL149836NHLBI NIH HHS R01HL149836NHLBI NIH HHS R01 HL151630NHLBI NIH HHS R01HL151630NHLBI NIH HHS R01 HL158668NHLBI NIH HHS R01HL158668NHLBI NIH HHS R01 HL164555NHLBI NIH HHS R01HL164555NHLBI NIH HHS R35 HL140039NHLBI NIH HHS R35HL140039NHLBI NIH HHS T32 HL007085NHLBI NIH HHS T32HL007085NHLBI NIH HHS UG3 HL151865NHLBI NIH HHS UG3/UH3HL151865NHLBI NIH HHS UH3 HL151865U.S. Department of Veterans Affairs I01BX005295
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40737485
PMCPMC12500162

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.