ArticleThe British journal of radiology2025
Impact of vessel size, dose levels, and body habitus on iodine quantification in cardiovascular photon-counting computed tomography.
Article in The British journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Understanding Photon-Counting CT: Physics, Detector Technology, and Image Reconstructions.Sensors (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectivesThis study evaluates the performance of a clinical dual-source photon-counting computed tomography (PCCT) system in quantifying iodine within calcified vessels, using 3D-printed phantoms with vascular-like structures lined with calcium.
methodsParameters assessed include lumen diameters (4, 6, 8, 10, and 12 mm), phantom sizes (S: 20 × 20 cm, M: 25 × 25 cm, L: 30 × 40 cm), and iodine concentrations (2, 5, and 10 mg/mL). Scans were performed with a cardiac high-pitch acquisition protocol at radiation dose levels of 5 and 10 mGy to systematically evaluate iodine quantification accuracy and spectral imaging performance.
resultsThe results indicate that for lumen diameters ≥6 mm, iodine quantification remains stable across all dose levels and smaller phantom sizes, where error remained consistently below 0.9 mg/mL. Furthermore, iodine quantification revealed a significant dependence on phantom size while selected radiation dose levels were insignificant. Virtual monoenergetic imaging at 70 keV showed stable performance for larger lumens (≥6 mm) with variations of 20.3 ± 13.2 HU across all conditions, while smaller lumens remained stable in medium to small phantoms.
conclusionsThese findings highlight the influence of lumen diameter, patient size, and radiation dose in optimizing PCCT protocols for spectral imaging. Results indicate that PCCT maintains stable and precise imaging performance across diverse patient anatomies, with robust differentiation of iodine and calcium in adjacent regions. ADVANCES IN KNOWLEDGE: This study demonstrates PCCT's potential to enhance spectral imaging in vascular applications, characterizing iodine quantification at relevant lesion sizes for vascular imaging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.