Evidence map›Paper›PMID 40737393›Full record

ArticleScience advances2025

The β

Drashya Sharma, Kira A Kohlbach, Robert Maples, J David Farrar

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Drashya SharmaDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0003-0309-7779
Kira A KohlbachDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0009-0000-3569-299X
Robert MaplesDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-5815-1210
J David FarrarDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-8584-7080

Funding

Adrenergic control of circadian rhythms in CD8 T cells responding to influenzaR01AI175217 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI John David FARRAR · 2023 to 2026
$2.3M
Adrenergic Control of Memory T Cells by Circadian RhythmsR21AI143248 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI FARRAR, JOHN DAVID · 2019 to 2020
$446k
Sympathetic neural control of T cell functionR56AI125545 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI FARRAR, JOHN DAVID · 2016 to 2016
$393k
NIAID NIH HHS R01 AI175217NIAID NIH HHS R21 AI143248NIAID NIH HHS R56 AI125545
6 · The paper itself

Abstract

Adaptive immune cells are regulated by circadian rhythms both under steady state conditions and during responses to infection. Cytolytic CD8

Indexed as

CD8-Positive T-LymphocytesCell DifferentiationCircadian RhythmReceptors, Adrenergic, beta-2AnimalsARNTL Transcription FactorsGene Expression RegulationMiceMice, KnockoutPeriod Circadian ProteinsSignal TransductionVesiculovirusADRB2 protein, mouseARNTL Transcription FactorsPeriod Circadian ProteinsReceptors, Adrenergic, beta-2

Identifiers

PMID40737393
PMCPMC12309669

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.