ArticleJournal of chemical information and modeling2025
Fast, Comprehensive, and User Customizable Macromolecule Interface Analysis with FACE2FACE.
Article in Journal of chemical information and modeling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Heterotropic regulation and negative homotropic cooperativity.FEBS open bio · 2026Article
- Untangling the Complexity of Binding Across Biomolecular Interfaces with Interaction Network Models.Methods in molecular biology (Clifton, N.J.) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Structural analysis of interfaces in macromolecular complexes is crucial to unveiling the mechanisms underlying molecular recognition. While several valuable computational tools exist for interface analysis, many web-based tools have limitations in input types, analysis comprehensiveness, or output customization, and there remains a need for an immediately accessible solution requiring no software installation, especially for users with limited computational skills. We have developed FACE2FACE, a user-friendly, fast, and comprehensive tool available as a web server for macromolecule interface analysis. FACE2FACE analyzes interfaces between proteins, nucleic acids, and other biological macromolecules or small molecules, providing extensive information that can be instantly visualized on the server interface and easily downloaded. The downloaded materials comprise files in formats that can be easily parsed and imported in spreadsheet applications as customizable contact maps and scripts to quickly visualize interface features in widely used applications such as PyMol and ChimeraX. Examples of FACE2FACE contributions to research projects are described.
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Registered trials
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