Evidence map›Paper›PMID 40737287›Full record

ArticleMolecular biology of the cell2025

FimX regulates type IV pilus localization via the Pil-Chp chemosensory system in

Taylor J Ellison, Ian Y Yen, P Lynne Howell, Courtney K Ellison

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Structural modeling reveals the mechanism of motor ATPase coordination during type IV pilus retraction.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Taylor J EllisonDepartment of Microbiology, University of Georgia, Athens, GA 30605.
Ian Y YenProgram in Molecular Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
P Lynne HowellProgram in Molecular Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Courtney K EllisonDepartment of Microbiology, University of Georgia, Athens, GA 30605.ORCID 0000-0003-3259-079X

Funding

Molecular mechanisms of physical interactions between bacteria and their surroundingsR35GM150916 · NIGMS · UNIVERSITY OF GEORGIA · PI Courtney Kathleen Ellison · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM150916
6 · The paper itself

Abstract

Type IV pili (T4P) are widespread dynamic appendages required for diverse prokaryotic behaviors, including twitching motility, biofilm formation, and DNA uptake leading to natural transformation. Although the components involved in T4P assembly and dynamics are largely conserved across divergent clades of bacteria, the mechanisms underlying T4P function and regulation differ significantly and remain poorly characterized outside of a select few model organisms. One understudied characteristic of T4P includes the spatial organization of T4P envelope-spanning nanomachines and how organizational patterns contribute to single-cell behaviors. The bacterial species

Indexed as

AcinetobacterBacterial ProteinsFimbriae, BacterialFimbriae ProteinsHistidine KinaseSignal TransductionBacterial ProteinsFimbriae ProteinsHistidine Kinase

Identifiers

PMID40737287
PMCPMC12415608

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.