ArticlePloS one2025
Evaluation of health effect on workers exposed to methyl bromide with prefrontal event-related potential.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Metabolomics analysis reveals diverse nematicidal metabolites from spore-forming bacteria.AIMS microbiology · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methyl bromide (MB) is a potent fumigant used to control pests in soil and agricultural products. As an ozone-depleting substance, MB has been largely replaced by safer alternatives. MB is highly toxic to humans and has been shown to adversely affect asymptomatic workers' central and autonomic nervous systems and vascular health. However, its impact on perceptual and cognitive abilities remains underexplored. In this study, we examined the effects of MB exposure on cognitive functions in asymptomatic workers. Event-related potential (ERP) indices, which reflect perceptual and cognitive processes, and urinary bromide ion (Br-) concentrations were assessed in 32 fumigators (study group) and 18 inspectors (control group) before and after fumigation. Post-work ERP latency and amplitude changes in inspectors were significant (P < 0.01), similar to those observed in healthy individuals. In contrast, ERP changes in fumigators were not significant compared to pre-work values; this suggests that MB negatively impacts cognitive health. Additionally, Br‑ levels in fumigators rose sharply after work (P < 0.001), while inspectors showed no such increase. The elevated Br- levels and nonenhanced ERP indices in fumigators after MB exposure indicate adverse health effects despite the absence of symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.