ArticleDiscover oncology2025
Androgen receptor as a potential therapeutic target in castration-resistant prostate cancer: a bibliometric analysis (2005-2024).
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Targeting Side Effects Associated with Androgen Deprivation Therapy Using Melatonin: A Randomized Trial on Hot Flashes and Sexual Health in Prostate Cancer Patients.Asian Pacific journal of cancer prevention : APJCP · 2026Trial
- Multimodal artificial intelligence in urologic precision oncology: from algorithm to translational medicine (a systemized narrative review).Frontiers in oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionThe androgen receptor (AR) remains a focal target in castration-resistant prostate cancer (CRPC) research, with recent studies providing valuable insights for advancing AR-targeted therapies. This study employs bibliometric methods to comprehensively analyze research trends in the CRPC and AR fields, identifying emerging hotspots and future directions.
methodsPublications from 2005 to 2024 were extracted from the Web of Science Core Collection (WoSCC). Bibliometric analysis and data visualization were performed using VOSviewer, CiteSpace, and the R package "Bibliometrix."
resultsA total of 3,149 publications authored by 15,704 researchers across 75 countries were analyzed. Publication output exhibited rapid growth over the past two decades. The United States dominated contributions, with the University of Washington ranking as the leading institution. Antonarakis, Emmanuel S. was the most prolific author, while Scher, Howard I. emerged as the most cited researcher. PROSTATE published the highest number of studies, whereas CANCER RESEARCH was the most cited journal. References co-citation analysis and keyword burst revealed persistent research emphasis on AR splice variants and CRPC drug resistance, with emerging investigations into novel membrane antigens representing current frontiers.
conclusionThis study delineates the evolving knowledge framework and shifting priorities in CRPC and AR research, offering strategic insights to guide future AR-targeted therapeutic development for CRPC.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.