Evidence map›Paper›PMID 40736866›Full record

ArticleEJNMMI physics2025

Motion correction of simultaneous brain PET/MR images based on tracer uptake characteristics.

Sheng-Chieh Chiu, Jose Angelo U Perucho, Yu-Hua Dean Fang

Abstract read
In one paragraph

Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sheng-Chieh ChiuDepartment of Biomedical Engineering, School of Engineering, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID http://orcid.org/0009-0002-4657-4926
Jose Angelo U PeruchoDepartment of Radiology, Heersink School of Medicine, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL, 35294, USA.ORCID http://orcid.org/0000-0001-6088-3173
Yu-Hua Dean FangDepartment of Radiology, Heersink School of Medicine, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL, 35294, USA. yfang@uabmc.edu.ORCID http://orcid.org/0000-0002-1039-7983

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Research Education ComponentP30AG066444 · NIA · WASHINGTON UNIVERSITY · PI DAVID M. HOLTZMAN · 2020 to 2026
$28.7M
UAB Alzheimer's Disease Research CenterP30AG086401 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Erik D Roberson · 2024 to 2026
$17.1M
THE XNAT IMAGING INFORMATICS PLATFORMR01EB009352 · NIBIB · WASHINGTON UNIVERSITY · PI Daniel Scott Marcus · 2009 to 2026
$9.3M
DRIVING PERFORMANCE IN PRECLINICAL ALZHEIMER'S DISEASER01AG043434 · NIA · WASHINGTON UNIVERSITY · PI ROE, CATHERINE M · 2012 to 2016
$2.4M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS P30 AG066444NIA NIH HHS P30 AG086401NIA NIH HHS R01 AG043434NIBIB NIH HHS R01 EB009352
6 · The paper itself

Abstract

backgroundSimultaneous PET/MR imaging enables precise anatomical localization and PET quantification by reducing PET-to-MR misalignments. However, involuntary motion during scans may still cause misalignment and quantification imprecision. Current mutual information (MI)-based co-registration methods do not account for the tissue-specific uptake patterns of PET and therefore could result in suboptimal alignment. To address this, we proposed a novel image co-registration method, namely the tracer characteristic-based co-registration (TCBC) method, which takes advantage of specific PET uptake patterns within a selected anatomical region to improve the image alignment and PET quantification.

resultsTCBC was evaluated using simulation and in vivo

conclusionsThe TCBC method reduces image misalignment, improves PET quantification, and may have a good potential for being applied to both research and clinical studies with simultaneous brain PET/MR. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Amyloid imagingMotion correctionPET quantificationSimultaneous PET/MR

Identifiers

PMID40736866
PMCPMC12311070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.