Evidence map›Paper›PMID 40736632›Full record

Observational studyClinical rheumatology2025

Evaluation of chronic orofacial pain and its relationship to the microvascular facial response in women with fibromyalgia.

María Del Carmen Villaverde-Rodríguez, María Correa-Rodríguez, Antonio Casas-Barragán, Rosa María Tapia-Haro, María Encarnación Aguilar-Ferrándiz

Abstract readObservational Study
In one paragraph

Observational study in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

María Del Carmen Villaverde-RodríguezPhD Biomedicine Program, Faculty of Health Sciences (Granada), University of Granada, Ave. de La Ilustración, 60, 18016, Granada, Spain.ORCID http://orcid.org/0000-0001-7809-9029
María Correa-RodríguezDepartment of Nursing, Faculty of Health Sciences (Granada), University of Granada, Ave. de La Ilustración, 60, 18016, Granada, Spain. macoro@ugr.es.
Antonio Casas-BarragánDepartment of Physiotherapy, Faculty of Health Sciences (Granada), University of Granada, Ave. de La Ilustración, 60, 18016, Granada, Spain.
Rosa María Tapia-HaroDepartment of Physiotherapy, Faculty of Health Sciences (Granada), University of Granada, Ave. de La Ilustración, 60, 18016, Granada, Spain.
María Encarnación Aguilar-FerrándizDepartment of Physiotherapy, Faculty of Health Sciences (Granada), University of Granada, Ave. de La Ilustración, 60, 18016, Granada, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent investigations suggest that central nervous system dysfunction and changes in peripheral blood microcirculation may explain the symptoms of fibromyalgia syndrome (FMS).

objectivesTo analyze the presence of chronic orofacial pain (COP) and assess facial skin microcirculation through surface temperature in women with FMS and healthy controls and to examine the relationship between peripheral facial skin temperature and oral symptomatology in FMS. DESIGN AND

methodsAn observational case-control study was conducted with 46 women with FMS and 44 healthy women. Infrared thermography was used to assess peripheral facial skin temperature, and facial pressure pain thresholds (PPTs), mouth opening measurement, the Craniofacial Pain and Disability Inventory (CF-PDI), and the Orofacial Visual Analog Scale (VAS) were used to assess COP.

resultsSignificant differences were found in orofacial-VAS (p ≤ 0.001), orofacial-PPTs (p ≤ 0.001), mouth opening (p = 0.003), and CF-PDI (p ≤ 0.001) between women with FMS and controls. No significant differences were identified in peripheral facial skin temperature between cases and controls, but significant associations were observed between facial thermography and oral symptomatology.

conclusionWomen with FMS exhibited greater orofacial pain and worse orofacial quality of life than healthy women, with associations between facial temperature and oral symptoms. Key Points • Women with fibromyalgia syndrome present chronic orofacial pain. • Mouth opening limitation and lower orofacial pressure pain threshold are observed. • The presence of orofacial pain has a negative impact on quality of life. • An association between facial thermography and oral pain symptoms is observed.

Indexed as

Chronic PainFacial PainFibromyalgiaMicrocirculationAdultCase-Control StudiesFaceFemaleHumansMiddle AgedPain MeasurementPain ThresholdQuality of LifeSkin TemperatureThermographyFibromyalgiaOrofacial painQuality of lifeThermography

Identifiers

PMID40736632
PMCPMC12397151

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.