Evidence map›Paper›PMID 40736624›Full record

ArticleEndocrine2025

Dual-energy X-ray absorptiometry and bioelectrical impedance analysis are useful for predicting metabolic syndrome and nonalcoholic fatty liver disease in children and adolescents.

Kyungchul Song, Eunju Lee, Hye Sun Lee, Hana Lee, Joon Young Kim, Youngha Choi, Hyun Wook Chae

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Article in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Kyungchul SongDepartment of Pediatrics, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea.ORCID 0000-0002-8497-5934
Eunju LeeBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0009-0003-7271-8310
Hye Sun LeeBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-6328-6948
Hana LeeDepartment of Pediatrics, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea.ORCID 0009-0002-6313-6135
Joon Young KimDepartment of Pediatrics, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea.ORCID 0000-0001-9595-3610
Youngha ChoiDepartment of Pediatrics, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea.ORCID 0000-0002-1607-6048
Hyun Wook ChaeDepartment of Pediatrics, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea. hopechae@yuhs.ac.ORCID 0000-0001-5016-8539

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAssessing body composition is essential for evaluating metabolic syndrome (MS) and nonalcoholic fatty liver disease (NAFLD). However, studies on the relationship between these conditions and dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA) in children and adolescents remain limited. This study aimed to investigate the associations between DXA and BIA parameters, and their utility in predicting MS and NAFLD in the youth.

methodsData from the Korea National Health and Nutrition Examination Survey 2009-2011 and 2022 were analyzed, including 1661 children and adolescents who underwent DXA, and 359 who underwent BIA; 712 were matched through propensity score matching. Pearson correlation and logistic regression analyses (with MS and NAFLD as dependent variables) were used to assess associations between DXA and BIA parameters. Predictive performance was evaluated using area under the receiver operating characteristic (ROC) curve comparisons.

resultsPearson correlation analyses revealed significant positive correlations between DXA and BIA parameters. In the logistic regression analyses, fat-related parameters were positively associated with MS and NAFLD, whereas muscle-related parameters showed negative associations, even after adjusting for age and sex. In the ROC analyses, BIA body fat mass had the highest predictive performance for both MS and NAFLD, followed by DXA body fat mass and percentage of body fat. Fat-related parameters were superior to muscle-related parameters for predicting MS and NAFLD.

conclusionBIA and DXA are useful tools for assessing MS and NAFLD in children and adolescents, and their complementary use enhances predictive accuracy, particularly through fat-related parameters.

Indexed as

Absorptiometry, PhotonElectric ImpedanceMetabolic SyndromeNon-alcoholic Fatty Liver DiseaseAdolescentBody CompositionChildFemaleHumansMaleNutrition SurveysPredictive Value of TestsRepublic of KoreaAbsorptiometry, photonChildElectronic impedanceMetabolic syndromeNonalcoholic fatty liver disease

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.