Evidence map›Paper›PMID 40736601›Full record

SynthesisNeuroradiology2025

Detection of large vessel occlusion using artificial intelligence tools: A systematic review and meta-analysis.

Julyana Dantas, Giovana Barros, Antonio Mutarelli, Caroline Dagostin, Pedro Romeiro, Giulia Almirón, Nicole Felix, Agostinho Pinheiro, Matheus A Bannach

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julyana DantasUniversidade Federal do Rio Grande do Norte, Natal, Brazil. julyana.dantas.114@ufrn.edu.br.ORCID http://orcid.org/0000-0002-0915-0932
Giovana BarrosUniversidade Estadual de Campinas, Campinas, Brazil.
Antonio MutarelliUniversidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Caroline DagostinUniversidade do Extremo Sul Catarinense, Criciúma, Brazil.
Pedro RomeiroUNIMA/AFYA - Centro Universitário de Maceió, Maceió, Brazil.
Giulia AlmirónUNIMES - Universidade Metropolitana de Santos, Santos, Brazil.
Nicole FelixUniversidade Federal de Campina Grande, Campina Grande, Brazil.
Agostinho PinheiroDepartment of Neurology, Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Matheus A BannachDepartment of Surgery, Division of Neurosurgery, Universidade Federal de Goiás, Goiânia, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeLarge vessel occlusion (LVO) accounts for a third of all ischemic strokes. Artificial intelligence (AI) has shown good accuracy in identifying LVOs on computed tomography angiograms (CTA). We sought to analyze whether AI-adjudicated CTA improves workflow times and clinical outcomes in patients with confirmed LVOs. MATERIALS AND

methodsWe systematically searched PubMed, Embase, and Web of Science for studies comparing initial radiological assessment assisted by AI softwares versus standard assessment of patients with acute LVO strokes. Results were pooled using a random-effects model as mean differences for continuous outcomes or odds ratio (OR) for dichotomous outcomes, along with 95% confidence intervals (CI).

resultsWe included 9 studies comprising 1,270 patients, of whom 671 (52.8%) had AI-assisted radiological assessment. AI consistently improved treatment times when compared to standard assessment, as evidenced by a mean reduction of 20.55 minutes in door-to-groin time (95% CI -36.69 to -4.42 minutes; p<0.01) and a reduction of 14.99 minutes in CTA to reperfusion (95% CI -28.45 to -1.53 minutes; p=0.03). Functional independence, defined as a modified Rankin scale 0-2, occurred at similar rates in the AI-supported group and with the standard workflow (OR 1.27; 95% CI 0.92 to 1.76; p=0.14), as did mortality (OR 0.71; 95% CI 0.27 to 1.88; p=0.49).

conclusionsThe incorporation of AI softwares for LVO detection in acute ischemic stroke enhanced workflow efficiency and was associated with decreased time to treatment. However, AI did not improve clinical outcomes as compared with standard assessment.

Indexed as

Artificial IntelligenceCerebral AngiographyComputed Tomography AngiographyIschemic StrokeHumansAcute strokeArtificial intelligenceIschemic strokeMeta-analysis

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.