Evidence map›Paper›PMID 40736219›Full record

SynthesisMovement disorders clinical practice2026

A Systematic Review of the Parkinson's Foundation Hospital Care Recommendations.

Ariane Veilleux Carpentier, Irene A Malaty, Peter A LeWitt, Hooman Azmi, Anne Brooks, Edward Pollak, Ellen L Air, Heather Simpson, Jaime Thomas, Florian P Thomas and 3 more

Abstract readSystematic ReviewReview
In one paragraph

Synthesis in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ariane Veilleux CarpentierCentre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.ORCID https://orcid.org/0009-0009-8166-6245
Irene A MalatyNorman Fixel Institute for Neurological Diseases, Gainesville, Florida, United States.ORCID https://orcid.org/0000-0001-6914-9223
Peter A LeWittDepartment of Neurology and Pharmacology, Sastry Foundation Endowed Chair in Parkinson Disease Research, Wayne State University School of Medicine, Detroit, Michigan, United States.ORCID https://orcid.org/0000-0002-4976-4445
Hooman AzmiHackensack University Medical Center, Hackensack, New Jersey, United States.
Anne BrooksParkinson's Foundation, United States.
Edward PollakHenry Ford Health, Detroit, Michigan, United States.
Ellen L AirHenry Ford Health, Detroit, Michigan, United States.
Heather SimpsonNorman Fixel Institute for Neurological Diseases, Gainesville, Florida, United States.
Jaime ThomasUniversity of Florida Health Shands Hospital, Gainesville, Florida, United States.
Florian P ThomasDepartment of Neurology and Neuroscience Institute, Hackensack University Medical Center, Hackensack, New Jersey, United States.
Lisa CocozielloHackensack University Medical Center, Hackensack, New Jersey, United States.
Sheera RosenfeldParkinson's Foundation, United States.
Michael S OkunNorman Fixel Institute for Neurological Diseases, Gainesville, Florida, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with Parkinson's disease (PwP) face increased risks of complications and longer hospital stays compared to the general population. Four major factors contribute to increased morbidity and mortality during hospitalization: medication timing errors, administration of harmful medications, restricted mobility, and dysphagia.

objectivesTo systematically review the literature on medication timing, contraindicated medications, mobility, and dysphagia in hospitalized PwP, and to evaluate the strength of evidence supporting the Parkinson's Foundation's consensus recommendations for inpatient care.

methodsA systematic review was conducted by searching MEDLINE and EMBASE databases up to February 1, 2024. Original research articles involving hospitalized PwP were included. The level of evidence for each Parkinson's Foundation recommendations was assessed.

resultsThe review included 33 studies. Multiple studies showed that medication errors were associated with longer hospital stays, motor deterioration, and increased mortality in PwP. Interventions such as electronic medical record alerts, staff education, and specialized PD units reduced medication errors. Limited evidence was found on the impact of immobility and dysphagia during hospitalization.

conclusionsThe evidence base supporting the Parkinson's Foundation's hospital care recommendations varies in strength. Recommendations regarding medication timing and avoiding harmful medications are supported by multiple observational studies, while those for mobility and dysphagia are primarily based on expert opinion. Implementing these recommendations through multidisciplinary interventions may improve hospital care quality for PD. However, more high-quality research, including randomized controlled trials, is needed to evaluate intervention impacts and address identified knowledge gaps.

Indexed as

HospitalizationParkinson DiseaseHumansdysphagiahospitalizationmedicationmobilityParkinson's disease

Identifiers

PMID40736219
PMCPMC12839495

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.