Evidence map›Paper›PMID 40736166›Full record

ArticleBiopolymers2025

In Vivo Wound Healing and Immune Response Studies of Chitosan Cryogels With Invertebrate Model Organism Galleria mellonella.

Sema Ekici, Serhat Kaya, Gürkan Durucu

Abstract read
In one paragraph

Article in Biopolymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sema EkiciFaculty of Sciences, Department of Chemistry, Hydrogel Research Laboratory, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Serhat KayaFaculty of Sciences, Department of Biology, Insect Physiology Laboratory, Canakkale Onsekiz Mart University, Canakkale, Turkey.ORCID https://orcid.org/0000-0002-0984-2824
Gürkan DurucuFaculty of Sciences, Department of Chemistry, Hydrogel Research Laboratory, Canakkale Onsekiz Mart University, Canakkale, Turkey.

Funding

Çanakkale Onsekiz Mart Üniversitesi FBA-2021-3548
6 · The paper itself

Abstract

In the present study, it was aimed to prepare single and double network chitosan (Ch) cryogels cross-linked with glutaraldehyde (G), which can be recommended for use as model wound dressings and hemostatic agents, and to reveal in vivo studies with Galleria mellonella. An in vivo study about Ch cryogels with these larvae was not declared in the literature, so our study is the first of its kind. G. mellonella was used to determine the effects of cryogels on immunity, oxidative stress, and wound healing. Cinnamic acid (CA) was loaded onto the cryogels, and the percent cumulative release data of CA were found to be in the range of 69%-80%. The results show that loading of CA onto [Ch-3]

Indexed as

ChitosanCryogelsMothsWound HealingAnimalsCinnamatesLarvaOxidative StressChitosanCinnamatescinnamic acidCryogelschitosan cryogelfull‐IPN cryogelG. mellonellahemostatic materialwound dressings

Identifiers

PMID40736166
PMCPMC12309346

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.