Evidence map›Paper›PMID 40736096›Full record

ArticleCoDAS2025

Response time, amplitude, and neural auditory maintenance in individuals with tinnitus: a comparative study.

Christine Grellmann Schumacher, Helinton Goulart Moreira, Denis Altieri de Oliveira Moraes, Larianny Rutzen Lazzari, Michele Vargas Garcia, Dayane Domeneghini Didoné

Abstract readComparative Study
In one paragraph

Article in CoDAS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christine Grellmann SchumacherDepartamento de Fonoaudiologia, Centro de Ciências da Saúde, Universidade Federal de Santa Maria - UFSM - Santa Maria (RS), Brasil.ORCID http://orcid.org/0000-0003-0732-6815
Helinton Goulart MoreiraDepartamento de Fonoaudiologia, Centro de Ciências da Saúde, Universidade Federal de Santa Maria - UFSM - Santa Maria (RS), Brasil.ORCID http://orcid.org/0000-0001-5212-7546
Denis Altieri de Oliveira MoraesDepartamento de Fonoaudiologia, Centro de Ciências da Saúde, Universidade Federal de Santa Maria - UFSM - Santa Maria (RS), Brasil.ORCID http://orcid.org/0000-0002-0600-2897
Larianny Rutzen LazzariDepartamento de Fonoaudiologia, Centro de Ciências da Saúde, Universidade Federal de Santa Maria - UFSM - Santa Maria (RS), Brasil.ORCID http://orcid.org/0009-0001-6034-3297
Michele Vargas GarciaDepartamento de Fonoaudiologia, Centro de Ciências da Saúde, Universidade Federal de Santa Maria - UFSM - Santa Maria (RS), Brasil.ORCID http://orcid.org/0000-0003-3779-349X
Dayane Domeneghini DidonéDepartamento de Fonoaudiologia, Centro de Ciências da Saúde, Universidade Federal de Santa Maria - UFSM - Santa Maria (RS), Brasil.ORCID http://orcid.org/0000-0002-0363-5613

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo verify and compare the response time, amplitude, and neural auditory maintenance of the central auditory pathway in subjects with and without tinnitus disorder.

methodsThis is an analytical, cross-sectional, and quantitative study approved by the Research Ethics Committee. The responses of Long Latency Auditory Evoked Potentials (LLAEP) with verbal stimuli were compared between 16 subjects with tinnitus disorder (Study Group - SG) and 12 subjects without tinnitus (Control Group - CG). The neural response time was evaluated by the latency of the P1, N1, P2, N2, and P300 potentials. The amplitude of these potentials was also analyzed. Neural response maintenance was verified through the duration values of the P300 component. The results were compared between the groups, considering a significance level of 5%.

resultsIn the comparison between the groups regarding the latency and amplitude values of the cortical potentials (P1, N1, P2, and N2), no statistically significant differences were observed (p>0.05). However, concerning the latency, amplitude, and duration of the P300 component between the groups, a statistically significant difference was observed for the latency variable, which was greater for individuals with tinnitus disorder (p<0.05).

conclusionIndividuals with tinnitus disorder have a longer neural response time for the P300 component, suggesting disorganization in central auditory processing.

Indexed as

Evoked Potentials, AuditoryReaction TimeTinnitusAcoustic StimulationAdultCase-Control StudiesCross-Sectional StudiesElectroencephalographyEvent-Related Potentials, P300FemaleHumansMaleMiddle Aged

Identifiers

PMID40736096
PMCPMC12315702

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.