Evidence map›Paper›PMID 40736086›Full record

GuidelineEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2025

Regionalization of the atria for 3D electroanatomical mapping, cardiac imaging, and computational modelling: a clinical consensus statement of the European Heart Rhythm Association and the European Association of Cardiovascular Imaging of the ESC.

Till F Althoff, Robert H Anderson, Christian Goetz, Steffen E Petersen, Patricia Martínez Díaz, Robin Nijveldt, Pal Maurovich-Horvat, Jeroen Bax, Sachal Hussain, Constanze Schmidt and 19 more

2 registry-linked trialsAbstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07320560 narecruitingnot on this mapstarted 2026, after this paper: background citation

Personalized Atrial Fibrillation Ablation Guided by Non-Invasive Global Mapping - the CURE-AF Pilot Study

TypeinterventionalSponsorGerman Heart InstituteRan2026 to 2027Enrolled45ConditionsAtrial Fibrillation (AF)ArmsNon-invasive mapping-guided ablation
NCT07358611 narecruitingnot on this mapstarted 2026, after this paper: background citation

ELectrocardiographic Imaging-guided Substrate Ablation in Patients With Atrial Fibrillation - a PILOT Study of a Personalized Therapy

TypeinterventionalSponsorHospital Clinic of BarcelonaRan2026 to 2027Enrolled30ConditionsAtrial Fibrillation (AF)ArmsNon-invasive mapping-guided ablation
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Intracardiac Echocardiography during Invasive Electrophysiological Procedures: a Scientific Statement of the European Heart Rhythm Association of the ESC, and the European Association of Percutaneous Cardiovascular Interventions of the ESC.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Guideline
  2. Review
  3. Review
  4. Review
  5. Role of interatrial connection ablation in re-entry dynamics: an in silico evaluation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  6. Article
  7. Perioperative atrial fibrillation after non-cardiac surgery - A narrative review.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Review
  8. Automated generation of ablation lesion masks: a unison of electro and optic flow mapping for persistent AF virtual cohorts.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Till F AlthoffArrhythmia Section, Department of Cardiology, Hospital Clínic, University of Barcelona, Carrer Villarroel 170, Barcelona 08036, Spain.ORCID 0000-0002-3289-2985
Robert H AndersonBiosciences Institute, Centre for Life, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.ORCID 0000-0001-5163-9021
Christian GoetzDepartment of Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany.ORCID 0009-0006-5222-4390
Steffen E PetersenWilliam Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University London, Charterhouse Square, London EC1M 6BQ, UK.ORCID 0000-0003-4622-5160
Patricia Martínez DíazInstitute of Biomedical Engineering, Computational Cardiac Modeling, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 1, Karlsruhe 76131, Germany.ORCID 0009-0006-9762-2982
Robin NijveldtDepartment of Cardiology, Radboud University Medical Center, Geert Grooteplein Zuid 10, Nijmegen 6525 GA, The Netherlands.ORCID 0000-0003-1530-6363
Pal Maurovich-HorvatDepartment of Radiology, Medical Imaging Centre, Semmelweis University, 2 Korányi Sándor St, Budapest 1083, Hungary.ORCID 0000-0003-0885-736X
Jeroen BaxDepartment of Cardiology, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.ORCID 0000-0001-7368-0500
Sachal HussainDepartment of Electrical, Electronic and Information Engineering 'Guglielmo Marconi', University of Bologna, Viale del Risorgimento, 2, Bologna, BO 40136, Italy.ORCID 0009-0008-1436-5218
Constanze SchmidtDepartment of Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany.ORCID 0000-0001-5897-237X
Diane E SpicerJohns Hopkins All Children's Hospital, Heart Institute, St Petersburg, FL, USA.ORCID 0000-0001-9885-3789
Damian Sanchez-QuintanaDepartamento de Anatomía Humana y Biología Celular, Facultad de Medicina, Universidad de Extremadura, Badajoz, Spain.ORCID 0000-0002-5374-8317
Cristiana CorsiDepartment of Electrical, Electronic and Information Engineering 'Guglielmo Marconi', University of Bologna, Viale del Risorgimento, 2, Bologna, BO 40136, Italy.ORCID 0000-0002-0289-9174
Olaf DösselInstitute of Biomedical Engineering, Computational Cardiac Modeling, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 1, Karlsruhe 76131, Germany.ORCID 0000-0003-4551-7970
Andreu M ClimentCOR Group, ITACA Institute, Universitat Politècnica de València, Camí de Vera, s/n, València 46022, Spain.ORCID 0000-0002-7260-8811
Blanca RodriguezDepartment of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford OX1 3QG, UK.
Ulrich SchottenDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, PO Box 616, Maastricht 6200 MD, The Netherlands.ORCID 0000-0003-1532-3315
Axel LoeweInstitute of Biomedical Engineering, Computational Cardiac Modeling, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 1, Karlsruhe 76131, Germany.ORCID 0000-0002-2487-4744
Maria S GuillemCOR Group, ITACA Institute, Universitat Politècnica de València, Camí de Vera, s/n, València 46022, Spain.
José-Ángel CabreraCardiology Department, Hospital Universitario Quirónsalud Madrid, European University of Madrid, c/ Diego de Velázquez, 1, Madrid 28223, Spain.ORCID 0000-0001-6380-1030
Jose L MerinoArrhythmia and Robotic EP Unit, La Paz University Hospital, P. Castellana, 261, Hospital General La Paz, Madrid 28046, Spain.ORCID 0000-0002-1737-1903
Adrianus P WijnmaalenDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Philippe B BertrandDepartment of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium.
Natasja de GrootDepartment of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Nicolas DervalIHU LIRYC, Electrophysiology and Heart Modeling Institute, Cardiac Electrophysiology and Stimulation Department, Fondation Bordeaux Université and Bordeaux University Hospital (CHU), Pessac-Bordeaux, France.
Maxim DidenkoClinic for Electrophysiology and Rhythmology, Heart and Diabetes Center North Rhine-Westphalia, University Hospital of Ruhr University Bochum, Bad Oeynhausen, Germany.
Erwan DonalCHU Rennes, University of Rennes, Inserm, LTSI-UMR 1099, Rennes F-35000, France.
Marc R DweckBHF Centre for Cardiovascular Science, University of Edinburgh, Little France Crescent, Little France, Edinburgh EH16 4SB, UK.
Siew Yen HoCardiac Morphology, Royal Brompton Hospital, London, UK.

Funding

European Union's Horizon 2020 research and innovation programme 860974
6 · The paper itself

Abstract

This clinical consensus document proposes standardized atrial segments for 3D imaging, electroanatomical mapping and computational modelling, based on anatomical, electrophysiological and clinical considerations, with precise definitions of regional borders allowing for reproducible and automated regionalization. 3D imaging and high-resolution electroanatomical mapping have become an integral part of cardiac electrophysiology and the management of patients with arrhythmias. However, to perform regional quantitative analyses and intra- and inter-individual, as well as cross-modality comparisons, a universal definition of atrial regions and their boundaries is required. While for the left ventricle there is already an established standardized regionalization (AHA 17-segment model), there is no such consensus for the atria. In a multi-disciplinary writing group consisting of cardiologists, cardiac electrophysiologists, cardiovascular imaging specialists, and anatomists as well as specialists in computational cardiac modelling from European Heart Rhythm Association and European Association of Cardiovascular Imaging, a standardized regionalization based on a 15-segment bi-atrial model was elaborated. This clinical consensus document will enable consistent regional analyses and homogeneous data acquisition across different centres and modalities, and may thus have a significant impact on atrial arrhythmia research and personalized treatment approaches based on individual arrhythmia patterns and phenotypes.

Indexed as

Electrophysiologic Techniques, CardiacHeart AtriaImaging, Three-DimensionalModels, CardiovascularAction PotentialsComputer SimulationConsensusHumansPredictive Value of TestsAtrial fibrillationAtrial regionsCardiac imagingCatheter ablationElectroanatomical mappingSegmentation

Identifiers

PMID40736086
PMCPMC12308486

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.