Evidence map›Paper›PMID 40736083›Full record

ArticleAnnals of medicine2025

Albumin: a novel biomarker for predicting intraoperative hypothermia in HSCR.

Xiaohui Huang, Mobai Ren, Junrong Pan, Ene Huang, Yanhong Li, Donghao Guo, Junjie Wang

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Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xiaohui HuangDepartment of Operating Room, Quanzhou Women's and Children's Hospital, Quanzhou, China.
Mobai RenSchool of Clinical Medicine, Shanghai Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Junrong PanDepartment of Operating Room, Quanzhou Women's and Children's Hospital, Quanzhou, China.
Ene HuangDepartment of Operating Room, Quanzhou Women's and Children's Hospital, Quanzhou, China.
Yanhong LiDepartment of Pediatric Endocrinology, Quanzhou Women's and Children's Hospital, Quanzhou, China.
Donghao GuoDepartment of Cardiology, Shanghai Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.ORCID 0000-0002-8300-8176
Junjie WangDepartment of Pediatric Endocrinology, Quanzhou Women's and Children's Hospital, Quanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntraoperative hypothermia is a significant life-threatening emergency during surgery in patients with Hirschsprung's disease (HSCR). The aim of this study is to explore the risk factors and predictors of intraoperative hypothermia in HSCR patients.

methodsThis cohort comprised 85 patients with HSCR who underwent surgery at Quanzhou Children's Hospital and the patients were divided into the intraoperative non-hypothermia group and the intraoperative hypothermia group. The study compared the characteristics of two groups and used univariate and multiple logistic regression analyses to assess the potential risk factors for intraoperative hypothermia. Models were adjusted for covariates, and interaction terms were evaluated for albumin (ALB) and intraoperative hypothermia. Subgroup analysis included stratification by sex and age. ROC analysis was applied to determine the optimal threshold for ALB.

resultsIn this retrospective study, 71 patients had intraoperative non-hypothermia and 14 patients had intraoperative hypothermia (83.5% versus 16.5%). Comparing the clinical characteristics between two groups, baseline core temperature, ALB and alkaline phosphatase (

conclusionALB is an independent risk factor for intraoperative hypothermia in HSCR patients. Further investments are required to explore its mechanisms.

Indexed as

Hirschsprung DiseaseHypothermiaIntraoperative ComplicationsSerum AlbuminBiomarkersChild, PreschoolFemaleHumansInfantLogistic ModelsMaleRetrospective StudiesRisk FactorsROC CurveBiomarkersSerum AlbuminalbuminHirschsprung’s diseaseIntraoperative hypothermia

Identifiers

PMID40736083
PMCPMC12312190

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.