Evidence map›Paper›PMID 40735981›Full record

ReviewCurrent HIV research2026

Accelerating Innovation: Advancing Opportunities in HIV Vaccine Development.

Carlos A Diazgranados, Thandi Onami, Pervin Anklesaria

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current HIV research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carlos A DiazgranadosHIV Vaccines, Global Health, Gates Foundation, Seattle, United States.
Thandi OnamiHIV Vaccines, Global Health, Gates Foundation, Seattle, United States.
Pervin AnklesariaHIV Vaccines, Global Health, Gates Foundation, Seattle, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review outlines the Gates Foundation's investments in support of global efforts dedicated to the research and development of a safe, highly effective, prophylactic HIV vaccine. Our current Collaboration for AIDS Vaccine Discovery (CAVD) portfolio encompasses a wide range of initiatives, including projects aimed at eliciting broadly neutralizing antibodies, enhancing CD8 T cell responses, and, through central service facilities, developing innovative analytical tools and animal models to assess immune responses. One central service facility also offers product development services to translate preclinical findings into clinical trials. Additionally, we are investing in platforms designed for the controlled release of HIV immunogens, simplifying complex vaccine regimens. Our ultimate objective is to develop a highly efficacious, safe, and durable vaccine that ensures broad access, uptake, and affordability. Furthermore, we emphasize the critical importance of fostering global partnerships, with a focus on supporting research capacity in low- and middle-income countries. By making intentional investments, we aim to stimulate sustainable research and development in the regions most affected by the HIV epidemic.

Indexed as

AIDS VaccinesHIV InfectionsVaccine DevelopmentAnimalsCD8-Positive T-LymphocytesHIV AntibodiesHumansAIDS VaccinesHIV AntibodiesAIDS vaccine discoveryantiretroviral therapyCD8 T cell responsesHIV epidemicpre-exposure prophylaxisvaccine regimens

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.