Trial reportCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025
Can Ultrasound-Guided in-Plane Puncture Technique Enhance the Precision of Femoral Artery Access? The Randomized PARFEM Trial.
Trial report in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06065943 (Department of Cardiology Wuerzburg University), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Department of Cardiology Wuerzburg University
Who cites it
1 citing paper in PubMed.
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Authors and funding
11 authors.
Funding
Abstract
backgroundUltrasound-guided puncture of the common femoral artery (CFA) is assumed to be more precise than conventional techniques without ultrasound. However, previous comparative studies have shown partly contradictory results with regard to success of ultrasound-guided puncture so that this method is not yet standard in transfemoral cardiac catheterization.
aimsThe PARFEM trial was performed to investigate whether an ultrasound-assisted in-plane technique using a needle guide could improve the precision of CFA puncture.
methodsThe study was conducted in 286 patients undergoing transfemoral cardiac catheterization. Patients were randomized 1:1, and femoral artery puncture was performed either using an ultrasound-guided in-plane technique with fluoroscopic marking of the center of the femoral head or a conventional approach. The primary endpoint was successful puncture of the CFA with the first attempt. In addition, the influence of the examiners' level of experience on puncture results was investigated.
resultsPrimary successful puncture of the CFA was achieved more frequently in the ultrasound group than in the control group: 79.6% versus 55.6%, odds ratio 3.25 [95% CI: 1.92-5.23], p < 0.001. This favorable effect of ultrasound guidance was independent of the examiners' level of experience. The success rate of ultrasound-guided sheath placement within the CFA was 97.2%, compared to 77.8% in the control group (p < 0.01).
conclusionsThe PARFEM trial demonstrated that in-plane ultrasound guidance can improve the precision of femoral puncture and reduce the occurrence of inadequate sheath placements. The results support the incorporation of this technique into standard practice for guiding transfemoral puncture.
trial registrationClinicalTrials.gov Identifier: NCT06065943.
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