Evidence map›Paper›PMID 40735615›Full record

ArticleFrontiers in microbiology2025

Antibacterial activity of endolysin LysP70 from

Kunzhong Zhang, Xuehui Zhao, Qing Cao, Qian Chong, Ziqiu Fan, Ji Zhi, Jiabing He, Jiayu Wang, Zhonglong Wang, Mingxia Cheng and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kunzhong ZhangCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Xuehui ZhaoCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Qing CaoCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Qian ChongCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Ziqiu FanCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Ji ZhiCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Jiabing HeCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Jiayu WangCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Zhonglong WangCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Mingxia ChengCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Min XiaoGansu Province Animal Disease Prevention and Control Center, Lanzhou, China.
Zijian WangGansu Province Animal Disease Prevention and Control Center, Lanzhou, China.
Huiwen XueCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.
Huitian GouCollege of Veterinary Medical, Gansu Agricultural University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endolysins, which are potential antimicrobial agents, can directly lyse gram-positive bacteria from the exterior. In this study, the endolysin gene derived from Listeria phage P70 was cloned, expressed, and purified, and designated LysP70. The antibacterial efficacy of LysP70 was comprehensively assessed through plate counting and electron microscopy. The findings indicate that LysP70 is composed of 315 amino acids and has a molecular weight of 34.2 kDa, structural stability, and peptidase activity. Successfully expressed and purified LysP70 demonstrated lytic activity against

Indexed as

antibacterial activitybacteriophageendolysinListeria monocytogenesLysP70

Identifiers

PMID40735615
PMCPMC12303923

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.