ArticlePakistan journal of medical sciences2025
Efficacy and safety of tiotropium combined with budesonide/formoterol in treating elderly patients with chronic obstructive pulmonary disease.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Efficacy and immune-inflammatory modulation of combined glucocorticoid and anti-tuberculosis therapy in patients with bronchial asthma and pulmonary tuberculosis.American journal of translational research · 2026Article
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6 authors.
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Abstract
Objective: This study aimed to assess the efficacy and safety of the combined tiotropium (TIO) and budesonide/formoterol (BUD/FORM) treatment in elderly patients with chronic obstructive pulmonary disease (COPD). Methods: Medical records of elderly patients with COPD who received treatment at the Third Affiliated Hospital of Zhejiang University of TCM from May 2023 to August 2024 were retrospectively analyzed. Elderly patients with COPD receiving TIO+BUD/FORM combination treatment (TIO+BUD/FORM group) and patients receiving TIO treatment alone were matched for age in a 1:1 ratio. The primary outcome of interest was the baseline change in pulmonary function at the 12 weeks follow-up. The secondary outcome was the incidence of adverse reactions. Results: This study included 114 patients. Post-treatment levels of forced vital capacity (FVC), FEV1 as a percentage of the predicted value (FEV1%pred), forced expiratory volume in one second (FEV1), and six-minute walk test (6MWT) in both groups increased compared to the baseline and were significantly higher in the TIO+BUD/FORM group compared to the TIO group ( Conclusions: Compared with TIO alone, TIO combined with BUD/FORM is more effective in improving pulmonary function in elderly patients with COPD without increasing adverse reactions.
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