ArticleBiological psychiatry global open science2025
Outdoor Air Pollution Is Related to Amygdala Subregion Volume and Apportionment in Early Adolescence.
Article in Biological psychiatry global open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Outdoor Air Pollution, Perivascular Space Morphology, and Cognition in Preadolescence.Biological psychiatry global open science · 2026Article
- Radon-related increases in depressive symptoms are explained by amygdala morphology and external locus of control.Neurotoxicology · 2026Article
- Associations between residential segregation, ambient air pollution, and hippocampal features in recent trauma survivors.Translational psychiatry · 2026Article
- Association between PMFrontiers in public health · 2026Article
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Abstract
Background: Outdoor air pollution exposure is associated with structural and functional brain differences and an increased risk for psychopathology. Although the neural mechanisms remain unclear, air pollutants may impact mental health by altering brain regions implicated in psychopathology, such as the amygdala. Here, we examined the association between ambient air pollution exposure and amygdala subregion volumes in 9- to 10-year-olds. Methods: Cross-sectional data from 4473 (55.4% male) Adolescent Brain Cognitive Development (ABCD) Study participants were leveraged. Air pollution exposure was estimated based on each participant's primary residential address. Using the CIT168 atlas, we quantified total amygdala and 9 subregion volumes from T1- and T2-weighted images. We investigated associations between criteria pollutants (i.e., fine particulate matter [PM Results: No significant associations were detected using single-pollutant models. Rather, in examining mixtures of exposures with PLSC, 1 latent dimension (52% variance explained) captured a positive association between calcium and several basolateral subregions. Latent dimensions were also identified for amygdala relative volume fractions (ranging from 30% to 82% variance explained), with PM Conclusions: PM
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