Evidence map›Paper›PMID 40735288›Full record

ArticleJournal of bone oncology2025

Effectiveness of rehabilitation treatment for bone metastasis patients without surgical intervention: A propensity score matching analysis.

Ryo Yoshikawa, Yasumitsu Fujii, Ryoga Kashima, Wataru Saho, Risa Harada, Daisuke Makiura, Katsuya Fujiwara, Junichiro Inoue, Yoshiki Takeoka, Ryoko Sawada and 6 more

Abstract read
In one paragraph

Article in Journal of bone oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ryo YoshikawaKobe University Graduate School of Medicine, Division of Rehabilitation Medicine, Kobe, Hyogo, Japan.
Yasumitsu FujiiKobe University Graduate School of Medicine, Division of Rehabilitation Medicine, Kobe, Hyogo, Japan.
Ryoga KashimaKobe University Graduate School of Medicine, Division of Rehabilitation Medicine, Kobe, Hyogo, Japan.
Wataru SahoKobe University Graduate School of Medicine, Division of Rehabilitation Medicine, Kobe, Hyogo, Japan.
Risa HaradaKobe University Graduate School of Medicine, Division of Rehabilitation Medicine, Kobe, Hyogo, Japan.
Daisuke MakiuraKobe University Hospital, Department of Rehabilitation Medicine, Kobe, Hyogo, Japan.
Katsuya FujiwaraKobe University Graduate School of Health Sciences, Department of Rehabilitation Science, Kobe, Hyogo, Japan.
Junichiro InoueKobe University Hospital, Department of Rehabilitation Medicine, Kobe, Hyogo, Japan.
Yoshiki TakeokaKobe University Graduate School of Medicine, Department of Orthopaedic Surgery, Kobe, Hyogo, Japan.
Ryoko SawadaKobe University Graduate School of Medicine, Department of Orthopaedic Surgery, Kobe, Hyogo, Japan.
Naomasa FukaseKobe University Graduate School of Medicine, Department of Orthopaedic Surgery, Kobe, Hyogo, Japan.
Keisuke OeKobe University Graduate School of Medicine, Department of Orthopaedic Surgery, Kobe, Hyogo, Japan.
Hitomi HaraKobe University Graduate School of Medicine, Department of Orthopaedic Surgery, Kobe, Hyogo, Japan.
Kenichiro KakutaniKobe University Graduate School of Medicine, Department of Orthopaedic Surgery, Kobe, Hyogo, Japan.
Toshihiro AkisueKobe University Graduate School of Health Sciences, Department of Rehabilitation Science, Kobe, Hyogo, Japan.
Yoshitada SakaiKobe University Graduate School of Medicine, Division of Rehabilitation Medicine, Kobe, Hyogo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence regarding the effectiveness of rehabilitation treatments in patients with bone metastases remains limited. This study evaluated the implementation and effectiveness of rehabilitation in patients with bone metastases who did not undergo surgery. This retrospective study included 200 patients with nonsurgically treated bone metastases at our institution. The patients were categorized into a rehabilitation group (R group, n = 61) and a non-rehabilitation group (N group, n = 139). Over the course of one month, we compared activities of daily living (ADL), assessed using the Barthel Index (BI), quality of life (QOL), measured using the EuroQoL-5 Dimension (EQ-5D), and demographic and clinical characteristics. Propensity score matching was conducted to minimize selection bias. After matching, 31 patients in each group were included in the analysis. No statistically significant differences were observed in baseline BI and EQ-5D scores between the two groups. In the R group, BI improved significantly from 80 (interquartile range [IQR]: 60-100) to 90 (IQR: 70-100), and EQ-5D improved from 0.444 (IQR: 0.282-0.608) to 0.608 (IQR: 0.533-0.768). In contrast, no improvements were observed in either score in the N group. Chemotherapy was identified as a significant factor associated with improvements in BI (odds ratio 4.03) and EQ-5D (odds ratio 5.29). Rehabilitation may be a valuable treatment option for nonsurgically treated patients with bone metastases, warranting further validation in prospective studies.

Indexed as

Activities of daily livingBone metastasisPropensity score matchingQuality of lifeRehabilitation

Identifiers

PMID40735288
PMCPMC12304898

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.