ArticleHealth science reports2025
Analgesia Quality and Duration of Fentanyl and Sufentanil Added to Bupivacaine in Spinal Anesthesia in Inguinal Hernia Surgery: A Double-Blind Parallel Randomized Controlled Trial.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: To compare the quality and duration of analgesia provided by Fentanyl and Sufentanil when added to 12-15 mg Bupivacaine 0.5% in spinal anesthesia for inguinal hernia surgery. Methods: In the present double-blind parallel Randomized Controlled Trial (RCT), 180 patients who were candidates for elective inguinal hernia surgery were divided into three groups using balanced-block randomization. The first group received 2.5 cc Bupivacaine with 0.5 cc (25 mg) Fentanyl, the second group received 0.5 cc (2.5 micrograms) of Sufentanil with 2.5 cc Bupivacaine, and the third group received 2.5 cc Bupivacaine with 0.5 cc normal saline. The pain score was evaluated by VAS (visual analog scale) at recovery and arrival in PACU, 2, 4, 6, and 12 h after the surgery. Results: A total of 60 subjects were allocated to each group. The mean (standard deviation) of pain score 2 h after surgery in Bupivacaine, Bupivacaine-Fentanyl, and Bupivacaine-Sufentanil were 1.73 (0.49), 1.10 (1.10), and 1.22 (1.25), respectively. These values 12 h after surgery were 2.76 (0.36), 2.97 (0.61), and 2.92 (0.56), respectively. The within-group comparison showed a significant increase in the pain score over time ( Conclusions: The pain-reducing effects of Sufentanil and Fentanyl, when combined with Bupivacaine, were significantly greater than those of Bupivacaine alone. However, this effect lasts only for up to 4 h after surgery, after which their efficacy diminishes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.