Evidence map›Paper›PMID 40735250›Full record

ArticleSchizophrenia research. Cognition2025

Theory-of-mind improvement in schizophrenia after integrative cognitive remediation: which patients benefit more?

Agurne Sampedro, Javier Peña, Pedro Sánchez, Naroa Ibarretxe-Bilbao, Nagore Iriarte-Yoller, Cristóbal Pavón, Natalia Ojeda

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Article in Schizophrenia research. Cognition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Agurne SampedroUniversity of Deusto, Faculty of Health Sciences, Department of Psychology, Bilbao, Spain.
Javier PeñaUniversity of Deusto, Faculty of Health Sciences, Department of Psychology, Bilbao, Spain.
Pedro SánchezHospital of Zamudio, Bizkaia Mental Health Network, Osakidetza Basque Health Service, Bilbao, Spain.
Naroa Ibarretxe-BilbaoUniversity of Deusto, Faculty of Health Sciences, Department of Psychology, Bilbao, Spain.
Nagore Iriarte-YollerBioaraba, New Therapies in Mental Health, Osakidetza Basque Health Service, Araba Mental Health Service, Alava Psychiatric Hospital, Vitoria-Gasteiz, Spain.
Cristóbal PavónBioaraba, New Therapies in Mental Health, Osakidetza Basque Health Service, Araba Mental Health Service, Alava Psychiatric Hospital, Vitoria-Gasteiz, Spain.
Natalia OjedaUniversity of Deusto, Faculty of Health Sciences, Department of Psychology, Bilbao, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Social cognition, and specifically theory of mind, is considered a key factor in predicting functional outcomes and quality of life in schizophrenia. Although cognitive remediation is an effective intervention for improving theory of mind, little is known about the factors that moderate this improvement. Therefore, the aim of this study is to identify moderators of theory-of-mind improvement in schizophrenia after integrative cognitive remediation (REHACOP). Data from two randomized controlled trials were used in this secondary analysis. The sample included 182 patients (experimental group = 94; active control group = 88) from the Mental Health Network in Álava (Spain). A comprehensive assessment of clinical symptoms, neurocognition, theory of mind, and functional outcome at baseline and follow-up was carried out. Hierarchical regression analyses were used to identify moderators of theory-of-mind improvement. Regardless of the patients' initial profiles, the REHACOP was effective in improving theory of mind (

Indexed as

Clinical symptomsPersonalized cognitive rehabilitationPersonalized medicinePsychosisSocial cognitionTheory of mind

Identifiers

PMID40735250
PMCPMC12305730

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.