ArticleFrontiers in public health2025
Health care resource use and costs associated with adult pneumococcal disease in the United States from 2017 to 2019, stratified by age and health risk: a retrospective cohort study.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Hospital Cost Components and Predictors inTropical medicine and infectious disease · 2026Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Adult pneumococcal disease (PD) represents a significant clinical and economic burden in the United States. Individuals with immunocompromising conditions and other chronic medical conditions, as well as those ≥65 years of age, have an increased risk of acute PD and its long-term complications. The aim of the current study was to describe the health care resource use and direct health care costs associated with invasive PD (IPD) and non-bacteremic pneumococcal pneumonia (NBPP) among adults in the United States, stratified by age group and health-based risk level. Methods: This was a retrospective study of administrative claims from the Merative™ MarketScan® Commercial Database from 2017 to 2019. The study population comprised individuals ≥18 years of age with ≥1 episode of IPD (with hospitalization) or NBPP (with or without hospitalization) during the study period. The study outcomes were the PD-associated health care resource use (outpatient visits and length of any hospitalizations, in days) and direct health care costs per episode. Results: The average health care resource use and direct costs associated with PD were significantly higher for IPD (mean [95% CI] overall cost $49,481 [$45,803-53,159] per episode; Conclusion: Targeting PD prevention efforts to high-risk groups based on age and/or health risk level could decrease the clinical and economic burden of adult PD in the US.
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