Evidence map›Paper›PMID 40735159›Full record

ArticleFood technology and biotechnology2025

Development and Application of a Novel 'Green' Antibacterial Black Garlic (

Mariah Sadaf, Anamika Das, Satadal Das, Subhankar Saha, Ketousetuo Kuotsu, Paramita Bhattacharjee

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Article in Food technology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mariah SadafDepartment of Food Technology and Biochemical Engineering, Faculty of Engineering and Technology, Jadavpur University, 700032 Kolkata, India.
Anamika DasDepartment of Food Technology and Biochemical Engineering, Faculty of Engineering and Technology, Jadavpur University, 700032 Kolkata, India.
Satadal DasDepartment of Microbiology, Peerless Hospital & B. K. Roy Research Centre, 70009 Kolkata 4, India.
Subhankar SahaDepartment of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, 700032 Kolkata, India.
Ketousetuo KuotsuDepartment of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, 700032 Kolkata, India.
Paramita BhattacharjeeDepartment of Food Technology and Biochemical Engineering, Faculty of Engineering and Technology, Jadavpur University, 700032 Kolkata, India.ORCID https://orcid.org/0000-0002-5620-1675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research background: Black garlic has been reported to have several health-promoting properties compared to fresh, raw garlic. The enzyme alliinase, which converts alliin to allicin, is deactivated at moderately high temperature, thus stripping away the typical pungent odour of fresh garlic during fermentation and rendering black garlic devoid of the typical garlic-like smell. To date, the antimicrobial activity of alliin-rich extract obtained from black garlic powder has not been reported. The objectives of this study are to explore the antibacterial/antifungal activity of alliin-rich black garlic extract against Experimental approach: Authenticated fresh garlic ( Results and conclusions: Soxhlet extraction of pulverized black garlic cloves using distilled water yielded an alliin-rich extract (6.4 mg/100 g garlic), which also contained additional bioactive organosulfur compounds with no reported toxicity. The antimicrobial potency (in terms of its minimum inhibitory concentration (MIC)) of the extract was evaluated against potent skin pathogens and was found to be ~15 µg/mL. The nanogels formulated with the alliin-rich extract showed shear thinning rheology and admirable sensory properties when tested by a panel. The Novelty and scientific contribution: This study is the first to report on a newly developed 'green' nanogel containing antimicrobial bioactive compounds, namely, organosulfur compounds (diallyl disulfide, diallyl trisulfide, methyl-allyl-disulfide and methyl-allyl-trisulfide). The nanogel showed promising epidermal wound-healing properties and is therefore promising in clinical applications against common and potent human skin pathogens.

Indexed as

alliin-rich extractantibacterial topical nanogelblack garlicepidermal wound healingskin pathogens

Identifiers

PMID40735159
PMCPMC12270587

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.