Automated Survey Collection with LLM-based Conversational Agents.

Objective: Traditional phone-based surveys are among the most accessible and widely used methods to collect biomedical and healthcare data, however, they are often costly, labor intensive, and difficult to scale effectively. To overcome these limitations, we propose an end-to-end survey collection framework driven by conversational Large Language Models (LLMs). Materials and Methods: Our framework consists of a researcher responsible for designing the survey and recruiting participants, a conversational phone agent powered by an LLM that calls participants and administers the survey, a second LLM (GPT-4o) that analyzes the conversation transcripts generated during the surveys, and a database for storing and organizing the results. To test our framework, we recruited 8 participants consisting of 5 native and 3 non-native english speakers and administered 40 surveys. We evaluated the correctness of LLM-generated conversation transcripts, accuracy of survey responses inferred by GPT- 4o and overall participant experience. Results: Survey responses were successfully extracted by GPT-4o from conversation transcripts with an average accuracy of 98% despite transcripts exhibiting an average per-line word error rate of 7.7%. While participants noted occasional errors made by the conversational LLM agent, they reported that the agent effectively conveyed the purpose of the survey, demonstrated good comprehension, and maintained an engaging interaction. Conclusions: Our study highlights the potential of LLM agents in conducting and analyzing phone surveys for healthcare applications. By reducing the workload on human interviewers and offering a scalable solution, this approach paves the way for real-world, end-to-end AI-powered phone survey collection systems.