ArticleArXiv2025
Effectiveness of Outer Hair Cells as Cochlear Amplifier: In Simple Model Systems.
Article in ArXiv, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Cochlear outer hair cells (OHCs) have two mechanosensitive elements: the hair bundle with mechanotrasducer channels and the piezoelectric lateral wall of the cell body. The present report examines how these elements interact with each other by incorporating OHCs into the simplest local cochlear models. In the frequency range, typically above 1 kHz, where capacitive conductance is greater than the ionic conductance, hair bundle (HB) conductance drives the piezoelectric cell body and amplified oscillation by countering viscous drag, while the cell body increases its stiffness owing to strain-induced polarization, elevating the resonance frequency. Since HB sensitivity is essential for amplification, the resonance is not pure piezoelectric, but semi-piezoelectric. In the lower frequency range, typically lower than 100 Hz, strain induced polarization contributes to drag and the HB sensitivity increases cell body stiffness.
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40735078PMC12306812What OpenQuestion holds
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