Evidence map›Paper›PMID 40734956›Full record

ArticleBMJ public health2025

Health-related quality of life among adult hypertensive patients globally: a systematic review and meta-analysis.

Baye Tsegaye Amlak, Addisu Getie, Mengistu Abebe Messelu, Temesgen Ayenew, Fisha Alebel GebreEyesus, Mamo Solomon Emire, Mihretie Gedfew, Setarg Ayenew Birhanie, Daniel Gashaneh Belay

Abstract read
In one paragraph

Article in BMJ public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Effectiveness of garlic clove (Bioinformation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Baye Tsegaye AmlakDepartment of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.ORCID https://orcid.org/0009-0001-3725-064X
Addisu GetieDepartment of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.ORCID https://orcid.org/0000-0002-0572-3414
Mengistu Abebe MesseluDepartment of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Temesgen AyenewDepartment of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Fisha Alebel GebreEyesusDepartment of Nursing, College of Medicine and Sciences, Wolkite University, Wolkite, Ethiopia.
Mamo Solomon EmireDepartment of Nursing, College of Medicine and Sciences, Wolkite University, Wolkite, Ethiopia.
Mihretie GedfewDepartment of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.ORCID https://orcid.org/0000-0003-0583-7793
Setarg Ayenew BirhanieDepartment of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Daniel Gashaneh BelayDepartment of Epidemiology and Biostatistics, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractObjective: This study aimed to assess the quality of life of hypertensive patients in the world. Design: Systematic review and meta-analysis using observational studies was done. Data sources: EMBASE, Scopus, PubMed/MEDLINE, Google Scholar and published and unpublished articles were used. Eligibility criteria: Observational studies reporting Health Related Quality of Life among hypertensive adults (>18 years) were included. Published studies, relevant abstracts and grey literature in English up to May 2024 were considered. Studies without the outcome of interest, inaccessible even after two email attempts, case reports, low-quality papers and review articles were excluded. Data extraction and synthesis: The data were extracted and cleaned using Microsoft Excel and analysed by STATA V.17. The protocol has been registered in the International Prospective Register of Systematic Reviews (PROSPERO) and given ID No. CRD42024562674.A random-effect meta-analysis technique was employed. The heterogeneity of the studies was assessed using Cochrane I Results: This review includes 22 studies with a total of 5447 study participants. The pooled mean SF-36 scores for hypertensive adults were 60.0 (95% CI 54.6 to 65.4) for physical component summary (PCS) and 60.1 (95% CI 54.2 to 66.1) for mental component summary (MCS). Based on trim-and-fill analysis, the bias-adjusted mean scores were 52.3% (95% CI 47.1% to 57.5%) for PCS and 46.4% (95% CI 41.3%-51.5%) for MCS. Conclusions: This meta-analysis revealed a significant negative impact of hypertension on both physical and mental health-related quality of life. The predicted mean scores, however, dropped to 52.3% for PCS and 46.4% for MCS after correcting for any publication bias using the trim-and-fill analysis. These findings warrant attention from health professionals, government officials, policymakers and the WHO. PROSPERO registration number: CRD42024562674.

Indexed as

Cardiovascular DiseasesmethodsPublic HealthSystematic Review

Identifiers

PMID40734956
PMCPMC12306259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.