Evidence map›Paper›PMID 40734952›Full record

ArticleApplications in engineering science2022

Development of an Ambulatory Extracorporeal Membrane Oxygenation System: From Concept to Clinical Use.

Dong Han, Aakash Shah, Morcos A Awad, Zhongjun J Wu, Bartley P Griffith

Abstract read
In one paragraph

Article in Applications in engineering science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Numerical Investigation of Gas Exchange Processes in Hollow-Fiber Membrane Bundles.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026
    Article
  2. Article
  3. Hemocompatibility Evaluation of a Novel Ambulatory Pulmonary Assist System Using a Lightweight Axial-Flow Pump.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2024
    Article
  4. Progress towards permanent respiratory support.Current opinion in organ transplantation · 2024
    Review
  5. Article
  6. Ambulatory 7-day mechanical circulatory support in sheep model of pulmonary hypertension and right heart failure.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dong HanDepartment of Surgery, University of Maryland School of Medicine, 10 South Pine Street, MSTF 436, Baltimore, MD, 21201, USA.
Aakash ShahDepartment of Surgery, University of Maryland School of Medicine, 10 South Pine Street, MSTF 436, Baltimore, MD, 21201, USA.
Morcos A AwadDepartment of Surgery, University of Maryland School of Medicine, 10 South Pine Street, MSTF 436, Baltimore, MD, 21201, USA.
Zhongjun J WuDepartment of Surgery, University of Maryland School of Medicine, 10 South Pine Street, MSTF 436, Baltimore, MD, 21201, USA.
Bartley P GriffithDepartment of Surgery, University of Maryland School of Medicine, 10 South Pine Street, MSTF 436, Baltimore, MD, 21201, USA.

Funding

Development and Pre-Clinical Trial Qualification of a Pediatric Pump-Lung System for ChildrenR01HL141817 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI GRIFFITH, BARTLEY P, WU, ZHONGJUN JON · 2018 to 2021
$3.1M
Shear-Induced Hemostatic Dysfunction and Bleeding in CF-VAD PatientsR01HL124170 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI GRIFFITH, BARTLEY P, WU, ZHONGJUN JON · 2015 to 2018
$2.0M
NHLBI NIH HHS R01 HL124170NHLBI NIH HHS R01 HL141817
6 · The paper itself

Abstract

Extracorporeal membrane oxygenation (ECMO) is a modality of life support for patients suffering from respiratory and/or cardiac failure. With the advances in membrane oxygenation and pump technology in the last two decades, ECMO has become safer and more durable for clinical use. Along with its overall use, there has been an increase in patients who require long-term ECMO support; either awaiting lung recovery or transplantation. Many of them are awake, participating in physical rehabilitation, and even ambulating while supported on ECMO. While the broader ECMO experience is applied to bed-restricted and mechanically ventilated patients, contemporary studies demonstrated that the artificial respiration provided by ECMO is compatible with freedom from adjunctive mechanical ventilation, ambulation, and exercise. With this in mind, our group set out to develop a novel ambulatory ECMO system to facilitate ambulation in patients supported on ECMO. This paper gives a brief overview of the development of this system, focusing on the journey from a laboratory concept to approval for clinical use by the Food and Drug Administration.

Identifiers

PMID40734952
PMCPMC12306593

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.