Evidence map›Paper›PMID 40734823›Full record

ArticleFrontiers in neurology2025

Reducing the acquisition time for magnetic resonance imaging using super-resolution image generation and evaluating the accuracy of hippocampal volumes for diagnosing Alzheimer's disease.

Nobukiyo Yoshida, Hajime Kageyama, Hiroyuki Akai, Satoshi Kasai, Kei Sasaki, Noriko Sakurai, Naoki Kodama

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nobukiyo YoshidaFaculty of Medical Technology, Department of Radiological Technology, Niigata University of Health and Welfare, Niigata, Japan.
Hajime KageyamaDepartment of Radiology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Hiroyuki AkaiDepartment of Radiology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Satoshi KasaiFaculty of Medical Technology, Department of Radiological Technology, Niigata University of Health and Welfare, Niigata, Japan.
Kei SasakiFaculty of Medical Technology, Department of Radiological Technology, Niigata University of Health and Welfare, Niigata, Japan.
Noriko SakuraiDepartment of Radiological Sciences, Faculty of Medical Science and Technology, Gunma Paz University, Gunma, Japan.
Naoki KodamaFaculty of Medical Technology, Department of Radiological Technology, Niigata University of Health and Welfare, Niigata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Brain magnetic resonance imaging (MRI) is important for diagnosing Alzheimer's disease (AD), and MRI acquisition time should be reduced. The current study aimed to identify which Pix2Pix-based super-resolution images can reduce errors associated with brain anatomical analysis with diffeomorphic deformation examination and MRI acquisition time. Methods: Fifty patients with dementia who uderwent scanning using a 3-T MRI scanner in the OASIS-3 database were used to construct a super-resolution network. Network training was performed using a scaled image (64 × 64) down-sampled from the original image as the input image and paired with the original high-resolution (256 × 256) supervised image. The hippocampal volume was measured using brain anatomical analysis with diffeomorphic deformation software, which employs machine learning algorithms and performs voxel-based morphometry. Peak signal-to-noise ratio (PSNR) and Multiscale structural similarity (MS-SSIM) score were used to objectively evaluate the generated images. Results: At Discussion: With super-resolution using the Pix2Pix network, the hippocampal volume can be accurately measured, and the MRI acquisition time can be reduced. The proposed method does not require special hardware and can be applied to previous images.

Indexed as

Alzheimer diseasebrain anatomical analysis using diffeomorphic deformationhippocampal volume measurementPix2Pix networksuper-resolution

Identifiers

PMID40734823
PMCPMC12306185

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.