Evidence map›Paper›PMID 40734795›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2025

Perme Score and Machine Learning for Detecting ICU-acquired Weakness: A Prospective Observational Cohort Study.

Lilian Elisabete Bernardes Delazari, Lígia Dos Santos Roceto Ratti, Adria Cristina da Silva, Melissa Sibinelli, Aline Maria Heidemann, Higor Luiz Marconi Montedioca, Emanuella Feitoza Dos Santos, Antonio Luís Eiras Falcão

Abstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Author Response: Due to Limitations in the Feasibility of the Perme Score it should not be Used to Classify Muscle Weakness in Intensive Care Unit Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  3. Due to Limitations in the Feasibility of the Perme Score, it should not be Used to Classify Muscle Weakness in Intensive Care Unit Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  4. Addressing ICU-acquired Weakness: A Call for Early Diagnosis and Intervention.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lilian Elisabete Bernardes DelazariDepartment of Physiotherapy, Clinical Hospital of UNICAMP, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID https://orcid.org/0009-0005-9594-3910
Lígia Dos Santos Roceto RattiDepartment of Physiotherapy, Clinical Hospital of UNICAMP, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-2095-8625
Adria Cristina da SilvaDepartment of Physiotherapy, Clinical Hospital of UNICAMP, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-0093-5506
Melissa SibinelliDepartment of Physiotherapy, Clinical Hospital of UNICAMP, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-0530-2342
Aline Maria HeidemannDepartment of Physiotherapy, Beneficência Portuguesa Hospital, Campinas, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-9989-4160
Higor Luiz Marconi MontediocaPostgraduate Student in Intensive Care Physiotherapy, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID https://orcid.org/0009-0004-7750-241X
Emanuella Feitoza Dos SantosPostgraduate Student in Intensive Care Physiotherapy, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID https://orcid.org/0009-0001-1559-1136
Antonio Luís Eiras FalcãoDepartment of Intensive Care Unit, Hospital São Luiz - Campinas, Rede D'Or; Full Professor (Livre-Docente) of Intensive Care Medicine, Faculty of Medical Sciences, University of Campinas (FCM-UNICAMP), Campinas, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-1630-7889

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Intensive care unit-acquired weakness (ICUAW) is a common complication in critically ill patients on prolonged mechanical ventilation (MV), impairing recovery and prolonging intensive care unit (ICU) stays. Standard diagnostic tools like the handgrip strength test (HGST) require patient cooperation and may be limited in critical settings. This study evaluated whether the Perme ICU Mobility Score, a multidimensional functional assessment, is associated with ICUAW and can serve as a screening tool using HGST as the diagnostic reference. Patients and methods: We conducted a prospective observational study in a Brazilian tertiary ICU from May 2021 to October 2023. We assessed adults (≥18 years) undergoing MV for ≥7 days who were clinically stable (pressure support 7 cm H Results: Among 97 patients, ICUAW was identified in 78.4%. Lower Perme Scores were significantly associated with ICUAW ( Conclusions: The Perme Score is a feasible, complementary screening tool for ICUAW. A cutoff ≤9 supports early functional risk stratification but should be interpreted alongside clinical context due to limited specificity and negative predictive value (NPV). How to cite this article: Delazari LEB, Ratti LSR, da Silva AC, Sibinelli M, Heidemann AM, Montedioca HLM,

Indexed as

Functional statusHand strengthICU-acquired weaknessMechanical ventilationMobility assessmentMuscle strength

Identifiers

PMID40734795
PMCPMC12302252

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.