ArticleHeart rhythm O22025
Low-voltage areas, atrial cardiomyopathy score, and outcomes in patients with preserved ejection fraction after catheter ablation of atrial fibrillation.
Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- HFA-PEFF and HHeart and vessels · 2026Article
- Ablate, or not to ablate left atrial low-voltage areas in atrial fibrillation patients?European heart journal open · 2026Article
- Multimodal Evaluation of Arrhythmogenic Substrate Predicts Atrial Fibrosis and Atrial Fibrillation Recurrence After Catheter Ablation.Journal of clinical medicine · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Left atrial low-voltage areas (LVAs) and the postprocedural atrial cardiomyopathy (AC) score-which incorporates echocardiographic data and brain natriuretic peptide levels-are linked to outcomes in patients undergoing catheter ablation of atrial fibrillation (AF). However, voltage mapping requires considerable time and cost, and the optimal prognostic predictor for patients with preserved left ventricular ejection fraction (LVEF) after AF ablation remains unclear. Objective: This study analyzed the relationship between LVAs, the AC score, and outcomes among patients with preserved LVEF after AF ablation. Methods: We retrospectively analyzed 270 patients with preserved LVEF who underwent AF ablation. Blood tests and transthoracic echocardiography were performed 2 weeks before and 3 months after ablation. We defined LVAs as regions with a bipolar peak-to-peak voltage of <0.50 mV. Patients were divided into 2 groups: no LVA (LVA size <5 cm Results: Multivariate analysis revealed that both the postprocedural AC score and the presence of LVA were independently associated with AF recurrence (hazard ratio [HR] = 1.49, Conclusion: The presence of LVA and the postprocedural AC score are associated with AF recurrence. However, the AC score is a more cost-effective and stronger predictor of cardiovascular events in patients with preserved LVEF after AF ablation than the presence of LVA.
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