Evidence map›Paper›PMID 40734716›Full record

ArticleACS catalysis2024

Engineering

Derek Aspacio, Emma Luu, Suphanida Worakaensai, Youtian Cui, Sarah Maxel, Edward King, Raine Hagerty, Alexander Chu, Derek Minn, Justin B Siegel and 1 more

Abstract read
In one paragraph

Article in ACS catalysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Derek AspacioDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, California 92697-3900, United States.
Emma LuuGenome Center, University of California, Davis, Davis, California 95616, United States.
Suphanida WorakaensaiDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, California 92697-3900, United States.
Youtian CuiGenome Center, University of California, Davis, Davis, California 95616, United States.ORCID 0000-0002-7138-2566
Sarah MaxelDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, California 92697-3900, United States.
Edward KingDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California 92697-3900, United States.
Raine HagertyDepartment of Biomedical Engineering, University of California, Irvine, Irvine, California 92697-3900, United States.
Alexander ChuDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, California 92697-3900, United States.
Derek MinnDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, California 92697-3900, United States.
Justin B SiegelGenome Center, University of California, Davis, Davis, California 95616, United States; Department of Chemistry and Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, California 95616, United States.
Han LiDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, California 92697-3900, United States; Department of Biomedical Engineering and Department of Biological Chemistry, University of California, Irvine, Irvine, California 92697-3900, United States.ORCID 0000-0002-6113-6433

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI YOUNG, THOMAS MICHAEL · 1987 to 2021
$50.1M
Enzymatic formation of the hydrocarbon skeletons underlying diterpenoid diversityR01GM076324 · NIGMS · IOWA STATE UNIVERSITY · PI PETERS, REUBEN JOHN · 2006 to 2019
$3.4M
Multi-scaled Modeling of Electrostatic and Polarization Effects in BiomoleculesR35GM130367 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI RAY LUO · 2019 to 2026
$3.0M
Engineering an unnatural redox cofactor (uRedox) system for efficient biosynthesis of medicinesDP2GM137427 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LI, HAN · 2019 to 2022
$2.4M
NIEHS NIH HHS P42 ES004699NIGMS NIH HHS DP2 GM137427NIGMS NIH HHS R01 GM076324NIGMS NIH HHS R35 GM130367
6 · The paper itself

Abstract

The future of biomanufacturing is dependent on rewiring biological systems to establish an alternative approach to our current chemical industries. However, a key limitation in biomanufacturing is that desired processes must rely on the same two redox cofactors as natural metabolism, nicotinamide adenine dinucleotide (phosphate) NAD(P)

Indexed as

biomimetic cofactordihydrolipoamide dehydrogenasenicotinamide mononucleotidenoncanonical redox cofactororthogonal pathway engineeringpyruvate dehydrogenase complexrational protein design

Identifiers

PMID40734716
PMCPMC12306648

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.