Evidence map›Paper›PMID 40734654›Full record

ArticleMovement disorders clinical practice2026

Subtype of the Freezing of Gait and Motor Function in Patients with Parkinson's Disease.

Katsuya Sakai, Tsubasa Kawasaki, Kichol Kim, Jyunya Ogawa, Yuya Yamaguchi

Abstract read
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Article in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Katsuya SakaiGraduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan.ORCID https://orcid.org/0000-0002-5708-9769
Tsubasa KawasakiDepartment of Physical Therapy, School of Health Sciences, Tokyo International University, Kawagoe, Japan.
Kichol KimDepartment of Rehabilitation, Kawaguchi Neurosurgery Rehabilitation Clinic, Osaka, Japan.
Jyunya OgawaDepartment of Rehabilitation, PDit Studio, Tokyo, Japan.
Yuya YamaguchiDepartment of Rehabilitation, PDit Studio, Tokyo, Japan.

Funding

Daiwa Securities Health Foundation
6 · The paper itself

Abstract

backgroundThe association between freezing of gait and motor function in Parkinson's disease is variable, and the results suggest the existence of subtypes.

objectivesThis study aimed to identify the subtypes of freezing of gait and motor function in patients with Parkinson's disease.

methodsSixty-one patients were included. This study assessed motor function using the freezing of gait questionnaire, the Unified Parkinson's Disease Rating Scale Part III. For statistical analyses, we conducted a cluster analysis using the freezing of gait and motor function. Analysis of covariance with age and L-dopa dosing as a covariate was performed for each cluster (P < 0.05).

resultsCluster 1 (N = 15) had the lowest freezing of gait scores compared to the other clusters, and its motor function scores were lower than those of cluster 3 (N = 9) (P < 0.05). Cluster 2 (N = 37) had moderate freezing of gait scores (vs. cluster 1, P < 0.05), and motor function showed lower scores than cluster 3 (P < 0.05); however, the score was not significantly different from that of cluster 1 (P > 0.05). Cluster 3 had moderate freezing of gait scores (vs. cluster 1, P < 0.05; vs. 2, P > 0.05) and higher motor function scores than the other clusters (P < 0.05); however, the freezing of gait score was not significantly different from that of cluster 2 (P > 0.05).

conclusionsThis study revealed new subtypes that presents with freezing of gait but high motor function in patients with Parkinson's disease.

Indexed as

Gait Disorders, NeurologicParkinson DiseaseAgedCluster AnalysisFemaleHumansLevodopaMaleMiddle AgedSeverity of Illness IndexSurveys and QuestionnairesLevodopacluster analysisfreezing of gaitmotor functionParkinson's diseasesubtype

Identifiers

PMID40734654
PMCPMC12839513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.