Evidence map›Paper›PMID 40734472›Full record

ArticleJournal of Alzheimer's disease : JAD2026

Dual sensory loss and cognitive performance among older adults in India.

Clarice A Myers, Wuyang Zhang, Niranjani Nagarajan, Jinkook Lee, A B Dey, Sharmistha Dey, Joyita Banerjee, Pranali Khobragade, Anushikha Dhankhar, Nicholas S Reed and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Clarice A MyersDepartment of Epidemiology, Cochlear Center for Hearing and Public Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Wuyang ZhangDepartment of Epidemiology, Cochlear Center for Hearing and Public Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Niranjani NagarajanOphthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
Jinkook LeeDepartment of Economics, Dana and David Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, USA.
A B DeyVenu Geriatric Institute, Venu Eye Hospital and Research Centre, Delhi, India.
Sharmistha DeyAll India Institute of Medical Sciences, New Delhi, India.
Joyita BanerjeeCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-3432-9782
Pranali KhobragadeCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Anushikha DhankharCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Nicholas S ReedDepartment of Epidemiology, Cochlear Center for Hearing and Public Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Joshua R EhrlichOphthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.

Funding

Leveraging a natural experiment to estimate the causal impact of blood sugar on dementia and cognition in IndiaR01AG051125 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jinkook Lee · 2015 to 2026
$26.8M
The Role of Hearing Loss in Health Care Outcomes.K23AG065443 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REED, NICHOLAS SALVATORE · 2020 to 2024
$943k
NIA NIH HHS K23 AG065443NIA NIH HHS R01 AG051125
6 · The paper itself

Abstract

BackgroundHearing loss (HL) and vision loss (VL) occur frequently among older adults and are independent risk factors for dementia, including in low- and middle-income countries (LMICs), where incident dementia is common. There is little research on the prevalence of dual sensory loss (DSL) and its association with cognitive health in LMICs.ObjectiveThis study investigates cross-sectional associations between DSL and cognitive performance among older adults in India.MethodsData (3,201) was analyzed from Wave I (2017-18) of the Longitudinal Aging Study in India (LASI) and Waves I (2017-2019) and II (2022-2024) of the Harmonized Diagnostic Assessment of Dementia for LASI (LASI-DAD). Better-ear hearing thresholds and better-eye distance visual acuity were used to create four categories: no sensory loss, HL only, VL only, and DSL. Global and cognitive domain factor scores were derived by factor analysis from the harmonized cognitive assessment protocol. Associations were assessed using multivariable linear regression models.ResultsOn average, participants were 69.7 years (±6.6) old and 50% were female. Forty percent had HL only (1,295), 8% had VL only (282), and 38% had DSL (1,217). Compared to those with no sensory loss, HL only and VL only scored 0.08 (95% CI: 0.02-0.17) and 0.10 (95% CI: 0.03-0.16) units lower in global cognition; those with DSL scored 0.18 (95% CI: 0.11-0.25) units lower. Similar patterns were observed across cognitive domains.ConclusionsGiven the association of DSL with cognitive function found, future research is needed to further characterize this association, test mechanistic pathways, and investigate possible causal effects.

Indexed as

CognitionCognitive DysfunctionHearing LossVision DisordersAgedAged, 80 and overAgingCross-Sectional StudiesFemaleHumansIndiaLongitudinal StudiesMaleMiddle AgedNeuropsychological TestsPrevalenceAlzheimer's diseasecognitive agingcognitive declinedementiahearingsensory impairmentsensory lossvision

Identifiers

PMID40734472
PMCPMC13002257

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.