Evidence map›Paper›PMID 40734353›Full record

ArticleBiomarkers in medicine2025

Serum asprosin, ox-LDL, and LOX-1 levels in patients with hypertension and their association with cardiovascular risk.

Çağla Özdemir, Hatice Solak

Abstract read
In one paragraph

Article in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Çağla ÖzdemirEvliya Çelebi Training and Research Hospital, Family Medicine Department, Kütahya Health Sciences University, Kütahya, Turkey.ORCID 0000-0002-9766-1918
Hatice SolakDepartment of Physiology, Faculty of Medicine, Kütahya Health Science University, Kütahya, Turkey.ORCID 0000-0002-3554-3051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimOur study aimed to investigate the relationship between oxidized low-density lipoprotein(ox-LDL), lectin-like ox-LDL receptor-1 (LOX-1), inducible nitric oxide synthase(iNOS), endothelin 1(ET-1), and asprosin levels with cardiovascular risk.

methodThe study is a case-control study. 177 patients (87 HT/90 controls) were included in the study. Biochemical parameters and blood pressure were measured. Cardiovascular risk was calculated using the European Society of Cardiology Cardiovascular Diseases (ESC CVD) risk calculator. Asprosin, oxLDL, LOX1R, ET1 and iNOS levels were measured using Enzyme-Linked ImmunoSorbent Assay (ELISA) kits in blood samples obtained after a minimum 8-hour fasting period. In statistical analyses,

resultsAge was significantly higher in the patient group than in the control group(

conclusionET1 and ox-LDL were lower in the HT group treated with antihypertensive therapy compared to the control group. Moreover, asprosin was found to be low in patients with high cardiovascular risk.

Indexed as

Cardiovascular DiseasesFibrillin-1HypertensionLipoproteins, LDLPeptide FragmentsScavenger Receptors, Class EAdipokinesAdultAgedBiomarkersCase-Control StudiesEndothelin-1FemaleHeart Disease Risk FactorsHumansMaleAdipokinesBiomarkersEndothelin-1FBN1 protein, humanFibrillin-1Lipoproteins, LDLOLR1 protein, humanoxidized low density lipoproteinPeptide FragmentsScavenger Receptors, Class Easprosinendothelin-1hypertensionlectin-like oxidized-LDL receptor-1Oxidized low-density lipoprotein

Identifiers

PMID40734353
PMCPMC12344817

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.