Evidence map›Paper›PMID 40733871›Full record

ArticleReports (MDPI)2023

Long-Term Outcome and Quality of Life in Patients Treated for Head and Neck Sarcoma during Pediatric Age: Considerations from a Series of 4 Cases.

Martina Buchignani, Arrigo Pellacani, Sara Negrello, Mattia Di Bartolomeo, Monica Cellini, Alessia Pancaldi, Alessandra Buttafoco, Camilla Migliozzi, Lorenzo Iughetti, Luigi Chiarini and 1 more

Abstract readCase Reports
In one paragraph

Article in Reports (MDPI), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Martina BuchignaniCranio-Maxillo-Facial Surgery Unit, Department of Medical and Surgical Sciences for Children & Adults, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy.
Arrigo PellacaniUnit of Dentistry and Maxillo-Facial Surgery, Surgery, Dentistry, Maternity and Infant Department, University of Verona, P.le L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0002-4880-5057
Sara NegrelloCranio-Maxillo-Facial Surgery Unit, University Hospital of Modena, Largo del Pozzo 71, 41124 Modena, Italy.ORCID 0000-0003-2242-945X
Mattia Di BartolomeoUnit of Dentistry and Maxillo-Facial Surgery, Surgery, Dentistry, Maternity and Infant Department, University of Verona, P.le L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0001-6142-7620
Monica CelliniPediatric Onco-Haematology Unit, Department of Medical and Surgical Sciences for Children & Adults, University of Modena and Reggio Emilia, Largo del Pozzo, 71, 41124 Modena, Italy.
Alessia PancaldiPediatric Onco-Haematology Unit, Department of Medical and Surgical Sciences for Children & Adults, University of Modena and Reggio Emilia, Largo del Pozzo, 71, 41124 Modena, Italy.
Alessandra ButtafocoPediatric Onco-Haematology Unit, Department of Medical and Surgical Sciences for Children & Adults, University of Modena and Reggio Emilia, Largo del Pozzo, 71, 41124 Modena, Italy.
Camilla MigliozziUnit of Psychology, Azienda Ospedaliero Universitaria di Modena, Largo del Pozzo 71, 41124 Modena, Italy.
Lorenzo IughettiPediatric Unit, Department of Medical and Surgical Sciences for Children & Adults, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy.ORCID 0000-0003-0370-7872
Luigi ChiariniCranio-Maxillo-Facial Surgery Unit, Department of Medical and Surgical Sciences for Children & Adults, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy.
Alexandre AnesiCranio-Maxillo-Facial Surgery Unit, Department of Medical and Surgical Sciences for Children & Adults, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy.ORCID 0000-0002-5281-6840

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric sarcomas are rare malignancies accounting for about 10% of solid tumors in childhood. Sarcomas represent a heterogeneous group of malignancies, especially they include Rhabdomyosarcoma (RMS) and Non-Rhabdomyosarcoma Type Sarcomas (STSNR). Therapeutic management of pediatric sarcomas is challenging. Multidisciplinary approach including chemotherapy, surgery and radiotherapy is the treatment of choice. The correct management of affected patients can be demanding, especially in terms of preserving a good quality of life (QoL). In the present study we described our experience with a series of patients diagnosed with head and neck non-metastatic sarcoma between January 1995 and December 2020, referred to Pediatric Oncology or to Maxillo-Facial Surgery of University Hospital of Modena and Reggio Emilia.The survivors were asked to complete questionnaires on health-related quality of life (HRQoL; PedsQL and EORTC QLQ-H&N 43). We found satisfactory results in terms of global HRQoL; although outstanding issues persist, such as deterioration in masticatory function, and speech. Long-term sequelae of multimodality treatment may lead to both significant aesthetic-functional and psychosocial implications that need to be further investigate during the whole the care pathway.

Indexed as

head and neck cancerHRQoLpediatricsarcomasurvival

Identifiers

PMID40733871
PMCPMC12225406

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.