Evidence map›Paper›PMID 40733748›Full record

ArticleVaccines2025

Evaluation of Anti-HB Levels in a Multi-Ethnic Cohort of Health Profession Students.

Lorenzo Ippoliti, Andrea Pizzo, Agostino Paolino, Luca Coppeta, Giuseppe Bizzarro, Cristiana Ferrari, Andrea Mazza, Claudia Salvi, Ersilia Buonomo, Fabian Cenko and 2 more

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In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lorenzo IppolitiDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Andrea PizzoDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Agostino PaolinoDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Luca CoppetaDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-2470-6107
Giuseppe BizzarroDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Cristiana FerrariDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-2292-3338
Andrea MazzaDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-9848-3236
Claudia SalviDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Ersilia BuonomoDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Fabian CenkoFaculty of Medicine, University "Our Lady of Good Counsel", 1000 Tirana, Albania.ORCID 0000-0001-7643-3695
Andrea MagriniDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Antonio PietroiustiFaculty of Medicine, Saint Camillus International University of Health Sciences, 00131 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the widespread implementation of childhood vaccination programmes, hepatitis B virus (HBV) infection remains an ongoing occupational risk for healthcare students. In multi-ethnic and international university settings, differences in vaccination programmes and immune responses must be considered. This retrospective study aimed to assess the prevalence of protective levels of anti-HBs among medical students at an international university in Rome, exploring associations with demographic and vaccination-related factors.

methodsData were collected from routine occupational health surveillance conducted in 2023. Anti-HB titres were measured in 507 students, and information on age, sex, country of birth, age at vaccination, and time since the last dose was analysed.

resultsOverall, 55.0% of students had antibody levels of at least 10 mIU/mL, indicating serological protection. Higher seroprotection rates were observed among students vaccinated in the first year of life compared to those vaccinated later. A significant decline in antibody titres was also associated with longer intervals since vaccination. Students born outside Europe tended to show lower levels of protection.

conclusionsThese results emphasise the importance of screening future healthcare professionals and continuously monitoring antibody titres to help reduce HBV infections.

Indexed as

healthcare workershepatitis Boccupational medicinevaccination

Identifiers

PMID40733748
PMCPMC12299118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.