Evidence map›Paper›PMID 40733719›Full record

ArticleVaccines2025

The Role of Anti-Interferon-α Autoantibodies in Severe COVID-19: Implications for Vaccination Prioritization.

Xin Rong Lim, Shiyu Liu, Hwee Siew Howe, Khai Pang Leong, Elampirai Elangovan, Chiung-Hui Huang, Kok Ooi Kong, Bernard Yu Hor Thong, Shawn Vasoo, Bernard Pui Lam Leung

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin Rong LimDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore 308433, Singapore.ORCID 0000-0002-1167-353X
Shiyu LiuDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Hwee Siew HoweDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore 308433, Singapore.ORCID 0000-0003-2656-136X
Khai Pang LeongDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Elampirai ElangovanNational Centre for Infectious Disease, Tan Tock Seng Hospital, Singapore 308442, Singapore.
Chiung-Hui HuangDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117549, Singapore.
Kok Ooi KongDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore 308433, Singapore.ORCID 0000-0003-2635-4715
Bernard Yu Hor ThongDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Shawn VasooNational Centre for Infectious Disease, Tan Tock Seng Hospital, Singapore 308442, Singapore.ORCID 0000-0001-7812-9881
Bernard Pui Lam LeungDepartment of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore 308433, Singapore.ORCID 0000-0002-1119-4934

Funding

Ng Teng Fong Healthcare Innovation Project #NTF_AUG2021_2C2_CR_05
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

autoantibodyCOVID-19 vaccinationIFN-αSARS-CoV-2type I interferon

Identifiers

PMID40733719
PMCPMC12298202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.