Evidence map›Paper›PMID 40733611›Full record

ArticleViruses2025

Characterization of a STAT-1 Knockout Mouse Model for Machupo Virus Infection and Pathogenesis.

Stephanie R Monticelli, Ana I Kuehne, Russell R Bakken, Susan R Coyne, Kenise D Lewis, Jo Lynne W Raymond, Xiankun Zeng, Joshua B Richardson, Zebulon Lapoint, Jennifer L Williams and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Stephanie R MonticelliViral Immunology Branch, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.ORCID 0000-0002-5031-2534
Ana I KuehneThe Geneva Foundation, Tacoma, WA 20817, USA.
Russell R BakkenThe Geneva Foundation, Tacoma, WA 20817, USA.
Susan R CoyneDevelopmental Diagnostics Branch, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Kenise D LewisChenega Corporation, Anchorage, AK 99503, USA.ORCID 0009-0007-2231-5563
Jo Lynne W RaymondPathology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.ORCID 0000-0002-2669-9062
Xiankun ZengPathology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.ORCID 0000-0003-3526-8755
Joshua B RichardsonCherokee Nation Integrated Health, Catoosa, OK 74015, USA.
Zebulon LapointCherokee Nation Integrated Health, Catoosa, OK 74015, USA.ORCID 0009-0008-1401-8670
Jennifer L WilliamsCherokee Nation Integrated Health, Catoosa, OK 74015, USA.
Christopher P StefanDevelopmental Diagnostics Branch, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.ORCID 0000-0003-4891-447X
Jeffrey R KugelmanCenter for Genome Science, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Jeffrey W KoehlerOperational Diagnostics Branch, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Andrew S HerbertThe Geneva Foundation, Tacoma, WA 20817, USA.ORCID 0009-0001-5256-7733

Funding

Defense Threat Reduction Agency CB11331
6 · The paper itself

Abstract

Machupo virus (MACV), a member of the

Indexed as

Arenaviruses, New WorldDisease Models, AnimalHemorrhagic Fever, AmericanSTAT1 Transcription FactorAnimalsBrainFemaleMiceMice, Inbred C57BLMice, KnockoutSpleenViral LoadStat1 protein, mouseSTAT1 Transcription Factorarenavirusarenavirus mouse modelsMachupo virusSTAT1

Identifiers

PMID40733611
PMCPMC12299389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.