Evidence map›Paper›PMID 40733608›Full record

ArticleViruses2025

Enterovirus Detection Trends Based on Respiratory Specimens from a Single Tertiary Hospital in Korea (2018-2024): A Retrospective Study Using Multiplex PCR Data.

Jeong Su Han, Sung Hun Jang, Jae-Sik Jeon, Jae Kyung Kim

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeong Su HanDepartment of Biomedical Laboratory Science, College of Health Sciences, Dankook University, Cheonan-si 31116, Republic of Korea.ORCID 0009-0008-7003-8422
Sung Hun JangDepartment of Medical Laser, Graduate School of Medicine, Dankook University, Cheonan-si 31116, Republic of Korea.ORCID 0009-0009-0934-8445
Jae-Sik JeonDepartment of Biomedical Laboratory Science, College of Health Sciences, Dankook University, Cheonan-si 31116, Republic of Korea.ORCID 0000-0001-8981-5705
Jae Kyung KimDepartment of Biomedical Laboratory Science, College of Health Sciences, Dankook University, Cheonan-si 31116, Republic of Korea.ORCID 0000-0002-1534-563X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteroviruses (EVs) cause broad clinical manifestations, particularly in children. Certain serotypes have been implicated in respiratory infections; however, epidemiological studies analyzing EV circulation based on clinical respiratory specimens are limited in Korea. This retrospective study evaluates EV detection patterns in respiratory specimens to demonstrate their clinical and epidemiological significance as respiratory pathogens in Korea. Respiratory samples collected from outpatient and hospitalized patients with respiratory symptoms at Dankook University Hospital between 2018 and 2024 were analyzed. EV detection patterns were analyzed by year, season, sex, and age. EVs were detected in 303/6292 respiratory specimens. The highest and lowest positivity rates were in 2018 (8.2%) and 2020 (1.6%), likely due to non-pharmaceutical interventions during the COVID-19 pandemic. The highest positivity rates were in summer and autumn, and in children aged 2-11 years and infants aged 0-1 years. EV positivity did not differ significantly between sexes. Significant differences were identified across years, seasons, and age groups. EVs can be detected in respiratory specimens from symptomatic patients and exhibit a marked seasonal distribution and elevated positivity rates in pediatric populations. Hence, EVs may act as atypical respiratory pathogens, underscoring the need for integrated public health surveillance and seasonal prevention strategies.

Indexed as

EnterovirusEnterovirus InfectionsRespiratory Tract InfectionsAdolescentAdultAgedChildChild, PreschoolCOVID-19FemaleHumansInfantInfant, NewbornMaleMiddle AgedMultiplex Polymerase Chain ReactionCOVID-19enterovirusepidemiologymultiplex PCRpediatricsrespiratory viruses

Identifiers

PMID40733608
PMCPMC12301017

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.